食管闭锁相关致病机制研究进展  

Genetic mechanisms of esophageal atresia

作　　者：王敏[1] 沈淳[1] 

机构地区：[1]复旦大学附属儿科医院外科,上海201102

出　　处：《中华小儿外科杂志》2016年第5期395-398,共4页Chinese Journal of Pediatric Surgery

摘　　要：食管闭锁是以食管的连续性中断为特点的先天性畸形，伴或不伴气管食管瘘，严重威胁新生儿的生命，是一种多因素参与的复杂疾病，其具体病因仍不明确，遗传机制复杂谆文将就其遗传相关致病因素进行综述，为进一步的研究提供参考。Esophageal atresia （EA） is congenital malformation characterized by a complete interruption of esophageal continuity with or without communications between esophagus and trachea. With a complex mode of inheritance, EA has an elusive etiology. This review offers a latest summary of diverse developmental processes in the context of developmental disorders for providing rationales for further studies.

关 键 词：食管闭锁 食管气管瘘 基因 

分 类 号：R725.7[医药卫生—儿科]