用无溶剂法制备二芳基磷氧化物的合成研究  

The Study for the Synthesis of Phosphine Betti Base by Three Components Condensation under Solvent-Free Conditions

作　　者：郑方映 刘风娇 丛榕[1] 薛琪慧 符金帅 匡志豪 江杰[1] 

机构地区：[1]海南师范大学化学与化工学院,海南海口571158

出　　处：《海南师范大学学报（自然科学版）》2016年第1期52-54,共3页Journal of Hainan Normal University（Natural Science）

基　　金：2015年海南师范大学创新创业训练项目(cxcyxj2015004;cxcyxj2015024);2014年研究生创新项目(Hsyx2014-39;Hsyx2014-38)

摘　　要：以β-萘酚,苯甲醛和二苯基氧磷为原料,一水合对甲基苯磺酸作有机酸作为催化剂,采用一锅法合成新的二芳基磷氧化物.结果表明,β-萘酚,苯甲醛和二苯基氧磷的三组分合成在高温无溶剂的条件中能够得到目标产物,该合成方法高效简单.A simple and efficient procedure has been developed for the preparation of diarylmethyl phosphine oxides by us- ing p-toluenesulfonic acid monohydrate as an organic acid catalyst. The methodology involved the one-pot condensation re- action of β-naphthol and aryl aldehydes and diphenylphosphine oxide under solvent-free conventional heating conditions. The present approach offered several advantages such as shorter reaction times, simple work-up, excellent yields and low- cost catalyst.

关 键 词：二芳基磷氧化物 对甲基苯磺酸一水合物 三组分一锅法 

分 类 号：O621.3[理学—有机化学]