抗HBc-IgM检测在乙型病毒性肝炎母婴垂直传播中的意义  

The significance of Anti-HBc-IgM testing in mother-to-child vertical transmission of Hepatitis B

作　　者：周立[1] 王瑞娟[1] 周秀芳[1] 王洁[1] 李玲[1] 

机构地区：[1]兰州市妇幼保健院新生儿科,甘肃兰州730030

出　　处：《中国医药科学》2016年第7期13-15,共3页China Medicine And Pharmacy

基　　金：甘肃省兰州市科技计划项目(2013-3-8)

摘　　要：目的通过检测乙肝孕妇及其新生婴儿抗HBc-ⅠgM水平,分析孕产妇及其新生婴儿抗HBc-ⅠgM水平关系,为早期发现新生儿宫内感染乙肝病毒提供依据。方法对兰州市妇幼保健院2012年1月-2014年12月住院孕产妇及其出生后2h内新生婴儿全部进行抗HBc-ⅠgM检测,对检测结果用SPSS 21.0进行相关性分析。结果母亲抗HBc-ⅠgM指标和子代HBc-ⅠgM指标存在较高的正相关。结论早期检测抗HBc-ⅠgM有助于早期发现新生儿乙肝,动态监测抗HBc-ⅠgM滴度是判断乙型肝炎病毒宫内传播的经济方便的检测指标。Objective In order to detective the HBV intrauterine infection of the newborn earlier, which by testing and analyze the level of the Anti-HBc-ⅠgM of maternity and her newborn. Methods Test for HBV Anti-HBc-ⅠgM serum markers of the mother and newborn which in maternity and child health care hospital of Lanzhou during 2 hours after birth from January 2012 to December 2014. Then analysis the correlation by SPSS 21.0. Results The positive rate of Anti-HBc–ⅠgM of mother and child is associated strongly. Conclusion It was an economical and convenient method by dynamic monitoring the Pregnant woman who infected HBV and her newborns＇ index of Anti-HBc–ⅠgM to find the newborn infected HBV earlier.

关 键 词：抗HBC-IGM 乙型病毒性肝炎 母婴垂直传播 

分 类 号：R512.6[医药卫生—内科学]