超声消融在治疗糖尿病性和非糖尿病性下肢动脉硬化闭塞症中的对比研究  

Comparative study on lower limb arteriosclerosis obliterans using ultrasound ablation between diabetic and non-diabetic patients

作　　者：毛燕丽[1] 雷鸣峰[1] 郭勇[1] 

机构地区：[1]通城县人民医院功能科,湖北省咸宁市437400

出　　处：《临床超声医学杂志》2016年第4期250-253,共4页Journal of Clinical Ultrasound in Medicine

摘　　要：目的探讨糖尿病性和非糖尿病性下肢动脉硬化闭塞症(ASO)行血管内超声消融的疗效。方法 76例糖尿病性ASO患者(糖尿病组)和80例非糖尿病性ASO患者(非糖尿病组)均采用超声消融治疗,观察两组患者病变部位、血管开通率、临床疗效及开通血管术后再闭塞情况。结果糖尿病组血管开通率为91.3%,非糖尿病组血管开通率为92.7%,两者比较差异无统计学意义;但糖尿病组临床总有效率低于非糖尿病组(76.3%vs.91.2%),差异有统计学意义(P<0.05)。开通血管术后随访糖尿病组17条发生血管再闭塞(16.2%),非糖尿病组5条发生血管再闭塞(5.6%),差异有统计学意义(P<0.05)。结论超声消融治疗ASO效果显著,虽然糖尿病患者消融疗效较非糖尿病患者略差,但超声消融仍可作为一种安全有效的治疗方法。Objective To study the effect of ultrasound ablation for lower limb arteriosclerosis obliterans（ASO） in diabetic and non-diabetic patients. Methods Seventy-six cases of diabetic patients with ASO（diabetes group） and 80 cases of non-diabetic patients without ASO （non-diabetes group） were enrolled in this study. All cases were treated using ultrasound ablation. References including the lesion location,rate of re-canalization,clinical effect,rate of re- occlusion after treatment were observed and recorded. Results The rate of re-canalization of diabetes group was 91.3%, which was close to that of non-diabetic group（92.7%）. Compared with non-diabetes group, patients in diabetes group had lower levels of clinical total effective rate（76.3% vs. 91.2%,P〈0.05）,and higher levels of re-occlusion rate（16.2% vs. 5.6%,P〈0.05）. Conclusion The treatment is effective for lower limb arteriosclerosis obliterans using ultrasound ablation. Due to their pathological feature,the effect of diabetic patients group is not as good as that of non-diabetic patients. Ultrasound ablation could be used as a safe and effective method for lower limb arteriosclerosis obliterans in both diabetic and non-diabetic patients.

关 键 词：超声消融 动脉硬化闭塞症 下肢 糖尿病 非糖尿病 

分 类 号：R543.5[医药卫生—心血管疾病] R445.1[医药卫生—内科学]