女贞子治疗骨质疏松作用及其机制的研究进展  

Research progress on effects and their mechanism of Ligustri Lucidi Fructus in treatment of osteoporosis

作　　者：郭鱼波 马如风 王丽丽[1] 刘海霞[1] 朱如愿 施荣枫[1] 赵丹丹[2] 莫芳芳[2] 高思华[2] 张东伟[2] 

机构地区：[1]北京中医药大学基础医学院,北京100029 [2]北京中医药大学糖尿病研究中心,北京100029

出　　处：《中草药》2016年第5期851-856,共6页Chinese Traditional and Herbal Drugs

基　　金：国家自然科学基金资助项目(81273995;81274140);教育部和国家外专局高等学校学科创新引智计划资助项目(B07007)

摘　　要：女贞子Ligustri Lucidi Fructus具有滋补肝肾作用,在古代用于骨痿等症的治疗,现代基础研究和临床研究也表明,女贞子在治疗骨质疏松方面有广阔的应用前景。通过查阅国内外相关文献,综述了关于女贞子治疗骨质疏松的相关实验研究和临床研究的进展,概括了女贞子和女贞子复方配伍治疗骨质疏松的作用机制,为进一步的实验研究和临床应用奠定了理论基础。Ligustri Lucidi Fructus （LLF）, which could nourish the liver and kidney, was used for the treatment of bone atrophy in ancient times. The current basic and clinical studies have shown that LLF had a broad application prospect in the treatment of osteoporosis. In this paper, by reviewing the related literature of home and abroad, we summarize the related experimental and clinical research progress of LLF and its compound on the treatment of osteoporosis, and clear their function mechanism, hoping to lay a theoretical foundation for further experimental study and clinical research.

关 键 词：女贞子 骨质疏松 滋补肝肾 骨瘘 复方配伍 

分 类 号：R285[医药卫生—中药学]