右美托咪定靶控输注在髋关节置换术中对血流动力学和术后苏醒时间的影响  

Dexmedetomidine TCI effects on hemodynamics and postoperative recovery time in hip replacement

作　　者：蒋永[1] 

机构地区：[1]内江市第一人民医院麻醉科,内江641000

出　　处：《北方药学》2016年第5期125-126,共2页Journal of North Pharmacy

摘　　要：目的:探讨右美托咪定靶控输注在髋关节置换术中对血流动力学和术后苏醒时间的影响。方法:选取46例在我院行全髋关节置换术的患者,按治疗方法分为观察组和对照组,每组23例。均采用全身麻醉手术。观察组术中采用右美托咪定联合丙泊酚靶控输注,对照组采用丙泊酚联合芬太尼麻醉,比较两组血流动力学指标和术后苏醒时间。结果:观察组输注8min、10min后血压、心率、BIS值均低于对照组(P<0.05),5min时血压高于对照组(P<0.05);与对照组相比,BIS70、BIS80、睁眼时间均缩短(P<0.05)。结论:在全髋关节置换术中采用右美托咪定靶控输注可有效维持血流动力学的稳定,缩短术后苏醒时间。Objective： To investigate dexmedetomidine target controlled infusion in total hip arthroplasty on hemodynamics and postoperative recovery time. Methods： 46 patients with total hip replacement in our hospital were divided into observation group and control group with 23 cases in each group. Are all used general anesthesia surgery. Observation group use of dexmedetomidine set combined with propofol target controlled infusion, propofot combined with fentanyl anesthesia is used in the control group, compared two groups of hemodynamics and postoperative recovery time. Results： in the observation group were injected with 8min, 10min after BP, HR and BIS values were lower than those of the control group （P 〈 0.05 ）, and 5 min when blood pressure is higher than the control group （P 〈 0.05 ）; after intubation and extubation in observation group, the blood pressure and heart rate were lower than that of the control group （P 〈 0.05 ）; compared with the control group, BIS70, BIS80, eye opening time was shortened （P 〈 0.05 ）. Conclusion： in total hip arthroplasty with dexmedetomidine fixed target controlled infusion can effectively maintain the stability of hemodynamics, and the postoperative recovery time can be shortened.

关 键 词：全髋关节置换术 右美托咪定 血流动力学 苏醒 

分 类 号：R614[医药卫生—麻醉学]