靶控输注舒芬太尼与瑞芬太尼复合麻醉对腹腔镜下结直肠癌根治术患者的影响对比研究  

Target controlled infu sion of sufentanil and remifentanil anesthesia on the comparative study on the effect of laparoscopic resection of colorectal cancer patients

作　　者：梁健群[1] 王展麟[1] 张建华[1] 卢先卿[1] 

机构地区：[1]肇庆市第一人民医院麻醉科,肇庆526100

出　　处：《北方药学》2016年第5期134-134,124,共2页Journal of North Pharmacy

摘　　要：目的：探究靶控输注舒芬太尼与瑞芬太尼复合麻醉对腹腔镜下结直肠癌根治术患者的影响。方法：选取我院于2013年11月~2015年11月收治的结直肠癌患者66例,全部患者择期在我院进行腹腔镜下结直肠癌根治术,随机分成A组与B组各33例,A组采用靶控输注舒芬太尼与瑞芬太尼复合麻醉,B组采用靶控输注舒芬太尼进行麻醉。对两组拔管时间、苏醒时间及恢复过程进行观察并记录,比较麻醉效果。结果：A组与B组的苏醒时间分别为（8.9±4.4）min及（17.2±7.8）min,A组与B组导管拔除时间分别为（13.3±3.1）min及（23.2±4.3）min,具有显著差异（P〈0.05）;A组在麻醉苏醒期间不良反应发生率明显低于B组（P〈0.05）。结论：采用靶控输注舒芬太尼与瑞芬太尼复合麻醉在腹腔镜下结直肠癌根治术中具有更好的效果,患者恢复情况更佳,不良反应较少,值得临床推广。Objective： To explore the target controlled infusion of sufentanil and remifentanil combined anesthesia of laparoscopic radical resection of colorectal cancer patients.Methods： 66 cases of colorectal cancer patients in November 2013 to 2015 in November in our hospital were selected in our hospital, all patients were undergoing elective in our hospital laparoscopic colorectal cancer radical operation were randomly divided into A group and B group with 33 cases in each. Group A by target controlled infusion injection of sufentanil and remifentanil anesthesia, group B with target controlled infusion of sufentanil anesthesia.Results： the recovery time of group A and group B respectively （8.9±4.4） rain and （17.2±7.8）min, A group and B group extubation time respectively （13.3±3.1 ） min and （23.2±4.3） rain, （P〈0.05）;The incidence of adverse reactions was significantly lower in group A than in group B （P〈O.05）. Conclusion： Using target controlled infusion of sufentanil and remifentanil anesthesia in laparoscopic colorectal cancer radical operation has a better effect, recovery of patients is better, and the adverse reactions less, worthy of clinical popularization and application.

关 键 词：靶向静脉输注 瑞芬太尼 舒芬太尼 结直肠癌 

分 类 号：R614[医药卫生—麻醉学]