季铵盐类消毒剂对多重耐药鲍曼不动杆菌杀菌效果的实验研究  

Experimental study on germicidal efficacy of quaternary ammonium salt disinfectants to multi- drug resistant Acinetobacter baumannii

作　　者：张为华[1] 龙铖彬 袁喆[1] 李崇志[1] 

机构地区：[1]重庆医科大学附属第一医院,重庆400016

出　　处：《中国消毒学杂志》2016年第5期408-410,共3页Chinese Journal of Disinfection

基　　金：重庆医科大学附属第一医院科研项目(HLJJ2011-17)

摘　　要：目的观察季铵盐类消毒剂对多重耐药鲍曼不动杆菌的杀灭效果。方法以临床分离的多重耐药鲍曼不动杆菌菌株为试验对象,选取苯扎溴铵消毒液和双链季铵盐消毒液,配成不同的浓度,作用至规定时间,利用悬液定量杀菌试验进行实验观察。结果 500 mg/L的苯扎溴铵消毒液和250 mg/L的双链季铵盐消毒液,分别作用30 s,对多重耐药鲍曼不动杆菌的杀灭率均能达到100%。结论季铵盐类消毒剂对多重耐药鲍曼不动杆菌有良好的杀灭效果。Objective To observe the Clinical isolated germicidal efficacy of quaternary ammonium salt disinfectants to multi - drug resistant Acinetobacter Baumannii. Methods Multiple drug resistant Acinetobacter Bat^manrrii strains were se- leted as the test objects. Benzalkonium bromide solutions and double chain quaternary ammonium salt disinfectants were di- luted into different concentrations respectively. Suspension quantitative germicidal test was used to carry out experimental observation. Results After 30 seconds, both benzalkonium bromide solutions （500 rag/L） and double chain quaternary am- monium salt disinfectants （250 mg/L） achieved the killing rate of 100% for multi - drug resistant Acinetobacter Baumannii. Conclusion The quaternary ammonium salt disinfectants shows excellent efficacy in killing multi - drug resistant acineto- bacter baumannii.

关 键 词：苯扎溴铵消毒液 双链季铵盐消毒液 多重耐药 鲍曼不动杆菌 

分 类 号：R187[医药卫生—流行病学]