冠状动脉慢血流现象与颈动脉硬化程度的相关性  

THE CORRELATION BETWEEN CAROTID ARTERIOSCLEROSIS AND CORONARY SLOW FLOW PHENOMENON

作　　者：张丽萍[1] 李世敬[2] 潘黎明[2] 王军[2] 王德昭[3] 

机构地区：[1]北京京煤集团总医院社区科,北京102300 [2]北京市门头沟区医院 [3]首都医科大学附属北京天坛医院

出　　处：《齐鲁医学杂志》2016年第2期200-202,共3页Medical Journal of Qilu

摘　　要：目的探讨冠状动脉慢血流（CSF）现象与颈动脉硬化程度的相关性。方法选取于我院住院并行冠状动脉造影检查的具有相似危险因素的CSF病人和冠状动脉血流正常（NCA）者各90例。应用血管回声跟踪（ET）技术评估双侧颈动脉硬化参数,包括僵硬度指数（β）、压力-应变弹性指数（Ep）、动脉顺应性（AC）和脉搏波传导速度（PWV）。测定血清超敏C反应蛋白（Hs-CRP）水平。通过线性回归分析,评价CSF病人颈动脉硬化程度与血清Hs-CRP水平的相关性。结果 CSF组β、Ep和PWV显著高于NCA组（t=2.189~2.806,P〈0.05）,AC显著低于NCA组（t=3.049,P〈0.01）。CSF组血清Hs-CRP水平显著高于NCA组（t=2.481,P〈0.05）。CSF病人血清Hs-CRP水平与β、Ep和PWV呈正相关（r=0.272~0.452,P〈0.01）,与AC呈负相关（r=-0.293,P〈0.05）。结论 CSF现象和颈动脉硬化程度具有一定的相关性。Objective To investigate the relationship between carotid arterial stiffness and coronary slow flow （CSF）. Methods Ninety patients with similar risk factor of CSF and 90 persons with normal coronary artery （NCA） detected by coronary angiography were recruited. Applying echo tracking （ET） technology, the stiffness parameters of bilateral carotid atherosclerosis including stiffness index （t3）, pressure strain elastic modulus （Ep）, arterial compliance （AC） and local pulse-wave velocity （PWV） were assessed. Serum levels of high-sensitivity C-reactive protein （Hs-CRP） were measured. Linear regression analysis was used to evaluate the correlation between carotid artery stiffness of CSF patients and Hs-CRP. Results In CSF group, the values of 13, Ep and PWV were significantly higher than that in the NCA group （t = 2.189- 2. 806, P〈 0.05）, and AC was lower （t = 3.049, P （0.01 ）. The levels of H s-CRP was significantly higher in CSF group versus the NCA （t = 2.481, P〈 0.05 ）. The levels of Hs- CRP was positively correlated with β, Ep and PWV in CSF group （r=0.272--0.452,P〈0.01）, but negatively correlated with AC （r = -0.293,P%0.05）. Conclusion The phenomenon of coronary slow flow has a certain association with the degree of stiffness in carotid artery arteriosclerosis.

关 键 词：颈动脉疾病 冠状动脉疾病 血流速度 超声检查 C反应蛋白质 

分 类 号：R541.4[医药卫生—心血管疾病]