急性心肌梗死3h内瑞替普酶溶栓与PCI治疗对左心功能影响的对比分析  

Comparing the Effect of Reteplase Thrombolytic Therapy and PCI Therapy on Left Ventricular Function in Acute Myocardial Infarction Within 3 Hours

作　　者：吕常智 

机构地区：[1]辽宁省丹东市第一医院心内科,辽宁省丹东市118000

出　　处：《中国动脉硬化杂志》2016年第5期507-509,共3页Chinese Journal of Arteriosclerosis

摘　　要：目的对比急性心肌梗死3 h内应用瑞替普酶溶栓治疗与急诊PCI治疗对梗死后心室重构及左心功能的影响。方法 98例患者分为瑞替普酶溶栓治疗组与急诊PCI治疗组,对两组患者心功能相关指标如NTPro BNP水平、收缩期末容量指数、舒张期末容量指数、射血分数、室壁运动积分指数进行比较。结果急性心肌梗死3 h内进行溶栓治疗与PCI治疗对氨基末端脑钠肽前体(NT-Pro BNP)水平、收缩期末容量指数、舒张期末容量指数、射血分数、室壁运动积分指数比较均无统计学差异(P>0.05)。结论急性心肌梗死3 h内溶栓治疗与PCI治疗对心功能影响程度相当,均为有效的再灌注治疗方法,降低并延缓心室重构发生,降低心力衰竭的发生率。对那些没有条件开展直接PCI治疗地区的急性ST段抬高型心肌梗死患者,进行溶栓并在适当时间内行PCI治疗,是一种可行的治疗策略。Aim To discuss the influence of reteplase thrombolytic therapy and emergency PCI treatment on ventricular remodeling and left ventricular function after acute myocardial infarction within 3 hours. Methods 98 patients were randomly divided into reteplase thrombolytic therapy group and emergency PCI treatment group. Compare cardiac function indexes of the two groups,such as NT-Pro BNP,ejection fraction,end systolic volume index,end diastolic volume index,ventricular wall motion score index. Results There were no significant differences between the two groups in NT-Pro BNP,ejection fraction,end systolic volume index,end diastolic volume index and ventricular wall motion score index（ P〉0. 05）. Conclusion These two treatments have the same effect on the left ventricular function in acute myocardial infarction within 3 hours. Both of them are effective reperfusion therapies. They can reduce and delay ventricular remodeling,and reduce the incidence of heart failure.

关 键 词：心肌梗死 瑞替普酶 PCI治疗 心功能 

分 类 号：R5[医药卫生—内科学]