HBsAg定量分析对慢性乙型肝炎抗病毒治疗的指导意义  

作　　者：杨笑萍 刘寿荣 

机构地区：[1]浙江中医药大学第二临床医学院,杭州310000 [2]杭州市西溪医院

出　　处：《中华实验和临床病毒学杂志》2016年第2期249-253,共5页Chinese Journal of Experimental and Clinical Virology

摘　　要：乙型肝炎病毒（hepatitis B vlrus,HBV）表面抗原（HBsAg）作为HBV感染的主要标志之一,近年来,其定量检测开始应用于HBV感染状态评估和指导抗病毒疗效分析领域.治疗过程中血清HBsAg水平的下降速度或HBsAg和HBVDNA水平共同下降可预测CHB患者抗病毒治疗的持续病毒学应答及治疗结束后HBsAg的血清学转换.本研究拟对HBsAg的定量分析以及对慢乙肝患者诊疗的指导意义做一综述.Objective In recent years, the which as one of the main markers of the hepatitis B quantitative detection of Hepatitis B surface antigen, virus infection, is applied to evaluate the infection of hepatitis B virus and direct the analysis of antiviral curative effect. Meanwhile, The descent speed of serum HBsAg or combine HBsAg with HBVDNA level in the treatment can predict the sustained virological response and the HBsAg seroconversion after antiviral treatment. This study is aimed to review the monitoring significance of Serum hepatitis B surface antigen quantitation for the diagnosis and treatment in chronic hepatitis B.

关 键 词：抗病毒治疗 HBSAG 定量分析 慢性乙型肝炎 HBV感染状态 持续病毒学应答 血清学转换 乙型肝炎病毒 

分 类 号：R512.62[医药卫生—内科学]