针刺肺经对大脑自发神经活动低频振荡振幅的影响  

Amplitude Changes of Low Frequency Fluctuation in Brain Spontaneous Nervous Activities Induced by Needling at Hand Taiyin Lung Channel

作　　者：周友龙[1] 苏程果[2] 刘守芳 靳翔愚[1] 段艳利 陈晓燕[5] 赵树华[5] 王权亮[5] 党长林[5] 

机构地区：[1]河南中医学院第三附属医院疼痛科,郑州450008 [2]郑州市第一人民医院疼痛科,郑州450009 [3]郑州市第九人民医院颈肩腰腿痛科,郑州450000 [4]河南省洛阳新区医院康复科,河南471000 [5]河南中医学院针灸推拿学院,郑州450000

出　　处：《中国中西医结合杂志》2016年第5期553-558,共6页Chinese Journal of Integrated Traditional and Western Medicine

摘　　要：目的观察针刺手太阴肺经腧穴引起的大脑自发神经活动低频振荡振幅(amplitude of low frequency fluctuations,ALFF)变化,初步探索手太阴肺经的脑功能网络。方法运用功能磁共振成像(functional magnetic resonance imaging,fMRI)技术,对16名健康志愿者进行纯静息态扫描(Rest1,R1)和针刺左侧手太阴肺经全经腧穴后留针状态扫描(acupuncture,AP)。对采集的fMRI数据均进行个体ALFF图像计算。结果R1状态下,右侧楔前叶、左侧顶下小叶、双侧额中回、双侧颞上回、左侧额下回、左侧额上回、左侧额内侧回等脑区表现出显著的ALFF增强。AP状态下,ALFF显著增强的脑区出现在右侧楔前叶、双侧额上回、小脑、双侧额中回、右侧额内侧回等。与R1状态比较,针刺手太阴肺经使ALFF在右侧胼胝体下回、右侧额下回显著增强,而在右侧中央后回、左楔叶、左侧颞上回、左侧颞中回等脑区则显著降低。结论针刺肺经腧穴会显著改变大脑皮层固有活动状态,尤其是右侧半球的胼胝体下回、额下回等区域ALFF显著增强。Objective To observe amplitude changes of low frequency fluctuation in brain spontaneous nervous activities induced by needling at Hand Taiyin Lung Channel, and to preliminarily explore the possible brain function network of Hand Taiyin Lung Channel. Methods By using functional magnetic resonance imaging（f MRI）,16 healthy volunteers underwent resting-state scanning（R1） and scanning with retained acupuncture at Hand Taiyin Lung Channel（acupuncture, AP）. Data of f MRI collected were statistically calculated using amplitude of low frequency fluctuations（ALFF）. Results Under R1 significantly enhanced ALFF occurred in right precuneus, left inferior parietal lobule, bilateral superior temporal gyrus, bilateral middle frontal gyrus, left superior frontal gyrus, left in-ferior frontal gyrus, left medial frontal gyrus. Under AP significantly enhanced ALFF occurred in right precuneus, bi-lateral superior frontal gyrus, cerebellum, bilateral middle frontal gyrus, right medial frontal gyrus, and so on. Com-pared with R1, needing at Hand Taiyin Lung Channel could significantly enhance ALFF in right gyrus subcallosum and right inferior frontal gyrus. Significant decreased ALFF appeared in right postcentral gyrus, left precuneus, left superior temporal gyrus, left middle temporal gyrus, and so on. Conclusion Needing at Hand Taiyin Lung Channel could significantly change fixed activities of cerebral cortex, especially in right subcallosal gyrus, right inferior frontal gyrus, and so on.

关 键 词：静息态功能磁共振成像 手太阴肺经 低频振荡振幅 脑功能网络 

分 类 号：R246[医药卫生—针灸推拿学]