右美托咪定用于眼部整形手术中的临床观察  

Clinical observation of Dexmedetomidine used in eye plastic surgery

作　　者：李泰平[1] 唐安[2] 

机构地区：[1]南京医科大学友谊整形外科医院药剂科,南京江苏210029 [2]南京医科大学友谊整形外科医院麻醉科,南京江苏210029

出　　处：《中国美容整形外科杂志》2016年第5期304-306,共3页Chinese Journal of Aesthetic and Plastic Surgery

摘　　要：目的评价右美托咪定在眼部整形手术中的应用效果。方法将拟行眼部整形术的120例患者随机分为局部麻醉组（对照组）和右美托咪定组（试验组），每组60例。试验组术前给予右美托咪啶1．0μg／kg，对照组常规行局部麻醉手术。全程监测血氧饱和度、心率、血压、心电图变化，以了解是否出现低氧血症和眼心反射，并记录脑电指数。对两组患者的镇静和焦虑程度进行评分，并记录手术进行时间和发生牵拉不适等情况。结果试验组患者术前和术后焦虑评分差异有统计学意义（P〈0．05）。对照组患者Ramsay镇静程度评分为Ⅰ级，试验组为Ⅱ级；试验组脑电指数为95～99，生命体征稳定，全程手术中与医师对答良好，与对照组相比，患者更为镇静，术中能很好配合，手术时间明显缩短，术中牵拉不适感也远比对照组少。结论右美托咪定用于眼部整形手术麻醉，效果确切，安全实用，值得临床推广使用。Objective To evaluate the application effect of Dexmedetomidine used in eye plastic surgery. Methods All 120 patients who planned to have eye plastic surgery were randomly divided into the local anes- thesia group （the control group） and the Dexmedetomidine group （the experimental group）, 60 patients for each group. Intravenous drip of Dexmedetomidine （ 1.0 μg/kg） was adopted for patients in the experimental group before local anesthesia, and regular local anesthesia for those in the control group. Blood oxygen satura- tion, heart rate, blood pressure, and electrocardiographic changes during the whole process were monitored so as to know whether hyoxemia and oculocardiac reflex occurred; meanwhile narcotrend index （NI） was recor- ded. The degrees of sedation and anxiety of patients were evaluated in both groups, and the operation time and the occurrence of traction discomfort were recorded. Results Statistical differences existed within the experi- mental group between patients＇ pre-operative and post-operative anxiety evaluations. The Ramsay sedation scale evaluation of patients in the control group was scored according to levels, by which the experimental group was level Ⅱ ; the NI of the experimental group fell in between 95 and 99. Patients in the experimental group were of stable vital signs during the whole operation, with nice answer with appropriate responses to the oculist. Com- pared with the control group, the patients in the experimental group were calmer and cooperated better with the oculist, even had obviously shorter operation time, and less traction discomfort. Conclusion Dexmedetomi- dine used in anesthesia of eye plastic surgery is effective, safe and practical, worthy to of recommendation its for clinical use.

关 键 词：眼部整形 右美托咪定 麻醉 外科手术 

分 类 号：R614[医药卫生—麻醉学]