乳腺癌患者淋巴清扫中应用两种示踪剂对示踪准确率、检出率及患者生活质量的影响  

Effects of methylene blue and nano-carbon suspension in lymph node dissection on the detection rate and life quality of patients with breast cancer

作　　者：赵启生[1] 杨贵义[1] 

机构地区：[1]湖北医药学院附属随州医院普外三科,湖北随州441300

出　　处：《东南大学学报（医学版）》2016年第1期108-111,共4页Journal of Southeast University(Medical Science Edition)

摘　　要：目的:研究乳腺癌患者淋巴清扫中应用两种示踪剂对示踪准确率、检出率及患者生活质量的影响。方法:选取2011年3月至2014年2月在我院进行淋巴清扫治疗的乳腺癌患者87例,按照随机分组法分为亚甲基蓝组(44例)和纳米炭混悬液组(43例),对两组患者的生活质量、示踪准确率、检出率进行分析。结果:两组患者检出率、灵敏度、准确率和假阴性率差异均无统计学意义(P>0.05)。两组患者生理功能评分差异无统计学意义(t=0.722,P>0.05);两组患者在生理职能、情感职能、社会功能、躯体疼痛、活力和精神健康等方面的得分差异均无统计学意义(P>0.05)。结论:乳腺癌患者淋巴清扫中应用两种示踪剂对示踪准确率、检出率影响较小,两种示踪剂下患者生活质量差异较小,因此在临床上亚甲基蓝和纳米炭混悬液均可作为示踪剂使用。Objective：To investigate the effects of different tracers applied in breast cancer patients with lymph node dissection on detection rate,accuracy and the quality of life. Methods：87 patients with breast cancer cured in our hospital from March 2011 to February 2014 were randomly divided into methylene blue group（n=44） and nano-carbon suspension group（n=43）. Quality of life,tracer detection rate and accuracy of two groups＇ patients were analyzed. Results：The difference of detection rate,sensitivity,accuracy and false negative rate between two groups were not significant （P〉0.05）. The score of physiological functions, emotional functioning, social functioning, body pain, vitality and mental health between two groups had no significant difference （P〉0.05）. Conclusion：Methylene blue and nano-carbon suspension applied in breast cancer patients with lymph node dissection have little effect on detection rate and accuracy, and have few influence on the quality of life. Therefore, methylene blue and nano-carbon suspension can be used as a tracer in clinical.

关 键 词：乳腺癌 淋巴结清扫 亚甲基蓝 纳米碳混悬液 生活质量 

分 类 号：R737.9[医药卫生—肿瘤]