疑似依维莫司药物洗脱支架致过敏1例  

A case of hypersensitivity fever induced by everolimus-eluting stent

作　　者：张洪洲[1] 吴延庆[1] 涂小丽[1] 龚韧[1] 陈琦[1] 徐劲松[1] 程晓曙[1] 

机构地区：[1]南昌大学第二附属医院心血管内科,南昌330006

出　　处：《临床心血管病杂志》2016年第5期535-536,共2页Journal of Clinical Cardiology

基　　金：国家自然科学基金地区科学基金资助项目(No:81260025);国家自然科学基金青年科学基金资助项目(No:30800467)

摘　　要：1病例资料患者,女,70岁,高血压史10余年,有血脂异常史,既往无其他药物及食物过敏史。2013年6月因＂反复心悸、胸闷8年,再发半年＂入院。体检：血压160/96mmHg（1 mmHg=0.133kPa）,双肺呼吸音清,无啰音,心界无扩大,心率52次/min,律齐,胸骨左缘第4肋间可闻及2/6级收缩期杂音。入院后查心脏彩超：主动脉瓣轻度狭窄并轻度反流,二尖瓣轻中度反流,左室肥厚。Here we reporteda case with a persistent mild to moderate fevertwenty hours after two everolimuseluting stents implantation.The reaction was successfully cured byoral antihistamine and glucocorticoids treatmentbefore all stent-bound everolimus was assumed to beeluted.No further hypersensitivity reaction occurred.The sequence of events and the treatment of this case indicate a causal relation ofeverolimus-eluting stent implantation and hypersensitivity fever.Therefore it should be carefully monitored for such adverse reaction when using everolimus-eluting stent.

关 键 词：药物洗脱支架 过敏 发热 

分 类 号：R541.4[医药卫生—心血管疾病]