复方α酮酸片对维持性血液透析患者营养状态和骨密度的影响  

Effect of Compound Alpha Keto Acid Tablets on Nutritional Status and Bone Mineral Density of Patients with Maintained Hemodialysis

作　　者：李小莉[1] 丁国华[1] 

机构地区：[1]武汉大学人民医院肾病内科,湖北武汉430000

出　　处：《河北医学》2016年第5期705-708,共4页Hebei Medicine

基　　金：湖北省自然科学基金资助项目(编号:2007ABA356)

摘　　要：目的:探讨复方α酮酸片对维持性血液透析患者营养状态和骨密度的影响。方法:收集我院收治的维持性血液透析患者90例,根据用药不同分为对照组和实验组,每组各45例,分别给予相应的药物治疗,治疗结束后,对所有患者的白蛋白、前白蛋白、血钙、血磷以及肌酐、尿素氮、跟骨骨密度水平进行检测。结果:与对照组相比,实验组患者各指标改善较为显著,具体表现为:实验组患者的PA、TP水平升高较为显著,差异具有统计学意义(P<0.05);实验组患者血钙水平升高较为显著,差异具有统计学意义(P<0.05);实验组患者血磷水平下降较为显著,差异具有统计学意义(P<0.05);实验组患者的骨密度升高较为显著,差异具有统计学意义(P<0.05)。结论:复方α酮酸片能够显著降低维持性血液透析患者白蛋白、前白蛋白、血钙水平,升高患者血磷以及骨密度,纠正患者的营养不良的状况,延长生存时间,对临床有指导意义。Objective：To investigate the effect of compound alpha keto acid tablets nutritional status and bone mineral density patients with maintained hemodialysis.Methods：Collected in our hospital maintenance hemodialysis patients 90 cases,and divided into experimental group and control group according to different drugs,each 45 cases were given corresponding drug treatment,after the end of treatment,for all patients of albumin,prealbumin,calcium,phosphorus and creatinine,urea nitrogen,calcaneal bone mineral density were detected.Results;Compared with the control group,the indexes of the patients in the experimental group improved more significantly,the specific performance;the patients in the experimental group,PA,TP level rise more significantly,the difference has statistical significance（P〈0.05）;serum calcium levels of the experimental group increased more significant differences were statistically significant（P 〈0.05）;experimental group patients,the serum phosphorus level decreased more significant,the difference has statistical significance（P〈0.05）;4 patients in the experimental group,bone density increased more significantly,and the difference is statistically significant（P〈 0.05）.Conclusion;Compound alpha keto acid tablets can significantly reduce maintenance hemodialysis patients albumin,prealbumin,serum calcium levels and increase serum phosphorus and bone density,patients to correct malnutrition status and prolong survival time,have guiding significance for clinic.

关 键 词：复方α酮酸片 维持性血液透析 营养状态 骨密度 

分 类 号：R692.5[医药卫生—泌尿科学]