自膨式裸支架LifeStent在髂动脉硬化闭塞疾病治疗中的疗效分析  

Short and Medium Term Results of Nitinol Self-Expending Stent(LifeStent) Implantation for Iliac Arteriosclerosis Obliteran

作　　者：陈彬[1] 高鹏[1] 于吉祥[1] 李禹[1] 孟冉冉[1] 惠菲菲[1] 杨彬[1] 

机构地区：[1]济宁市第一人民医院血管外科,山东济宁272000

出　　处：《中国普外基础与临床杂志》2016年第5期586-589,共4页Chinese Journal of Bases and Clinics In General Surgery

摘　　要：目的评价腔内技术对治疗髂动脉狭窄闭塞性疾病的近中期疗效。方法回顾性分析济宁市第一人民医院2011年6月至2014年6月期间使用第2代自膨式裸支架Life Stent(美国,巴德)置入治疗的64例髂动脉硬化闭塞疾病患者(共75条患肢)的临床资料,分析其保肢率、通畅率、并发症发生率等。结果本组患者平均年龄为68岁,按泛大西洋协作组织共识(TASC)Ⅱ分型,TASCⅡA型患肢11条,TASCⅡB型患肢26条,TASCⅡC型患肢29条,TASCⅡD型患肢9条。术前踝肱指数为0.29±0.20,术后复查踝肱指数为0.94±0.16,术后踝肱指数明显高于术前(P<0.01)。术后随访(22±10)个月,失访5例。1年、2年的一期累积通畅率分别为79%和60%、二期累积通畅率分别为91%和84%、保肢率分别为96%和94%。围手术期发生并发症5例,并发症发生率为7.8%,无手术相关死亡及严重并发症发生。结论第2代自膨式裸支架Life Stent治疗髂动脉狭窄闭塞疾病的近中期临床疗效较满意,远期疗效尚需进一步观察。Objective To evaluate short and medium term results of nitinol self-expending stent（LifeS tent） implantation for iliac arteriosclerosis obliteran. Methods The clinical data of 75 limbs iliac artery occlusions in 64 patients from June 2011 to June 2014 in this hospital were analyzed retrospectively. The postoperative ankle brachial index（ABI）, limb salvage rate, primary and secondary patency rate, and postoperative complications were evaluated. Results There were 75 limbs iliac artery occlusions in 64 patients（54 males and 10 females）, 11 lesions were type A of TASC Ⅱ, 26 lesions were type B of TASC Ⅱ, 29 lesions were type C of TASC Ⅱ, 9 lesions were type D of TASC Ⅱ. The postoperative ABI was significantly higher than that preoperative ABI（0.94±0.16 versus 0.29±0.20, t=-24.7, P〈0.01）. The following-up time was（22±10） months, 5 patients were lost to follow-up. In 12 and 24 months after surgery, the cumulative primary patency rates were 79% and 60%, respectively, the cumulative second patency rates were 91% and 84%, respectively, the limb salvage rates were 96% and 94%, respectively. Complications occurred in 5 patients（7.8%）. There was no severe complications and inhospital mortality. Conclusion Clinical efficacy of short and medium term is satisfactory by nitinol self-expending stents implantation（Life Stent） for iliac arteriosclerosis obliteran, but long term efficacy remains to be further studied.

关 键 词：动脉闭塞性疾病 髂动脉 自膨式裸支架 支架成形术 

分 类 号：R654.3[医药卫生—外科学]