高致病性猪蓝耳病疫苗对猪瘟和蓝耳病抗体水平的影响  

Effects of High Pathogenic Porcine Reproductive and Respiratory Syndrome( HP-PRRS) Vaccine on Serum Antibody Level of Classical Swine Fever( CSF) and PRRS

作　　者：李彩虹[1] 何文[1] 何子双 

机构地区：[1]南充职业技术学院,四川南充637102 [2]大北农集团重庆区技术服务部,重庆405200

出　　处：《安徽农业科学》2016年第8期110-112,共3页Journal of Anhui Agricultural Sciences

摘　　要：[目的]研究高致病性猪蓝耳病(High pathogenic porcine reproductive and respiratory syndrome,HP-PRRS)疫苗对猪瘟(Classical swine fever,CSF)和猪蓝耳病(Porcine reproductive and respiratory syndrome,PRRS)抗体水平的影响。[方法]采用ELISA方法检测3个猪场248份血清的猪瘟(CSF)和猪蓝耳病(PRRS)抗体,并对CSF抗体阻断率和PRRS抗体的S/P值进行多重比较。[结果]猪场A(没有免疫HP-PRRS疫苗)、猪场B和猪场C(都免疫HP-PRRS毒株JXA-1R疫苗)全群猪的CSF抗体阳性率分别为94.29%、53.93%和66.29%,其PRRS抗体阳性率分别为42.86%、91.01%和82.02%。猪场A、C母猪和全群猪的CSF抗体阻断率极显著高于猪场B(P<0.01);猪场A的育肥猪和全群猪的CSF抗体阻断率显著高于猪场C。猪场B的母猪、后备母猪、育肥猪、全群猪PRRS抗体S/P值极显著高于猪场A、C(P<0.01),猪场C的育肥猪、全群猪PRRS抗体S/P值显著高于猪场A(P<0.05)。[结论]免疫HP-PRRS毒株JXA-1R疫苗可能引起猪群CSF抗体水平降低,PRRS抗体水平提高。[ Objective ] To research the effects of high pathogenicporcine reproductive and respiratory syndrome （HP-PRRS） vaccine on serum antibody level of classical swine fever （CSF） and PRRS. [ Method] The CSF and PRRS serum antibody of 248 pigs from three herds were detected by CSF and PRRS antibody ELISA kit; and the multiple comparisons of blocking rate of CSF antibody （BRCA） and PRRS S/P value were analyzed by LSD program of IBM SPSS statistics software. [ Result] The positive percent rates of CSF antibody in herds A （without HP-PRRS vaccine） ,B and C （with HP-PRRS JXA-1R vaccine both） were 94.29% ,53.93% and 66.29% ,respectively. And the positive percent rates of PRRS antibody were 42.86% ,91.01% ,82.02% ,respectively. The BRGA of sows and all pigs in herds A and C were higher than herd B （P 〈0. 01 ）, and that of finishing and all pigs in herd A were higher than herd C （P 〈 0. 01 and P 〈 0. 05 ,respectively） . The PRRS S/P value of sows, gilts,finishing and all pigs in herd B were higher than herd A and C （P 〈0.01 ） ,and that of finishing and all pigs in herd C were higher than herd A （P 〈 0. 05 ）. [ Conclusion] The CSF serum antibody level is remarkably downgraded and the PRRS antibody raised by HP-PRRS JXA-1R vaccine.

关 键 词：高致病性猪蓝耳病疫苗 猪瘟抗体 猪蓝耳病抗体 

分 类 号：S858.28[农业科学—临床兽医学]