实时组织弹性成像和三维超声造影在乳腺肿块鉴别诊断中的应用价值  

Differential diagnostic value of real-time tissue elastography and three dimensional ultrasound imaging in breast lumps

作　　者：李明慧[1] 刘翼[1] 柳莉莎[1] 李平新[1] 陈琦[1] 

机构地区：[1]新疆医科大学附属肿瘤医院超声科,乌鲁木齐830011

出　　处：《中华医学杂志》2016年第19期1515-1518,共4页National Medical Journal of China

基　　金：新疆医科大学科研创新基金

摘　　要：目的探讨实时组织弹性成像和三维超声造影在乳腺肿块鉴别诊断中的应用价值。方法选取新疆医科大学附属肿瘤医院2012年12月至2014年12月的126例（180个）乳腺肿块患者进行回顾性分析，使用分层随机方法分为实时组织弹性成像检查组、三维超声造影检查组和两者联合检查组，每组各42例（60个），以病理结果为金标准，得到不同方法的诊断灵敏度、特异度及符合率，并对各方法进行比较。结果超声造影下的良性肿块多呈点状、线状和结节状增强，增强边界多平滑；恶性肿块以不均匀、高增强为主，增强边界多数欠清或不清。弹性成像检查组和三维超声造影检查组进行比较，灵敏度、特异度和符合率差异无统计学意义（64．7％比73．5％、69．2％比76．9％、66．7％比75．0％，均P〉0．05）；两者联合检查组的灵敏度、特异度和符合率优于弹性成像检查组和三维超声造影检查组，差异有统计学意义（97．1％、92．3％和98．3％，均P〈0．05）。结论三维超声造影联合实时组织弹性成像对乳腺肿块的诊断具有较高价值。Objective To investigate the real-time tissue elastography and 3D contrast-enhanced uhrasonography（CEUS） in breast lumps differential diagnostic value. Methods A total of 126 patients （180 lumps） with breast mass were retrospectively analyzed from December 2012 to December 2014 in Tumor Hospital Affiliated To Xinjiang Medical University. All patients were divided into three groups by using stratified random method. Each group was detected by real-time tissue elastography,3D CEUS and two joint inspection. Each group of 42 cases （60 lumps） was confirmed by the pathological results as gold standard. Diagnostic sensitivity, specificity and coincidence rate of different methods were compared. Results The benign masses of ultrasound contrast showed the punctate, linear and nodular enhancement, and the border of enhancement was smooth. The malignant tumors were mainly dominated by uneven and high enhancement. There was no statistical difference in sensitivity, specificity and coincidence rate between elastography group and 3D CEUS group （64. 7% vs 73.5% ,69. 2% vs 76. 9% ,66. 7% vs 75.0% ,all P 〉 0. 05 ）. The sensitivity, specificity and coincidence rate of two joint inspection group were higher than those of elastography group and 3D CEUS group,the differences were statistically significant （97.1% ,92. 3% and 98.3 % , all P 〈 0.05 ）. Conclusion 3D CEUS combined with real-time tissue elastography is of high value in the diagnosis of breast masses.

关 键 词：超声检查 弹性成像技术 乳腺疾病 

分 类 号：R445.1[医药卫生—影像医学与核医学] R737.9[医药卫生—诊断学]