彩色多普勒超声与磁共振成像在胎脑发育异常中的临床应用研究  

Clinical application of ultrasonic and magnetic resonance imaging in the intrauterine fetal encephalodysplasia

作　　者：王存强[1] 王爱华[1] 贺顺岭 申国琴[1] 谷丽萍[1] 顾韵泽 Yuan Ziyang Wang Wenna Liu Xiaokun 

机构地区：[1]河南省新乡市第一人民医院,453000

出　　处：《实用医技杂志》2016年第5期453-455,共3页Journal of Practical Medical Techniques

基　　金：河南省新乡市重点科技攻关计划(ZG12017)

摘　　要：目的探讨彩色多普勒超声联合磁共振检查在胎脑发育异常中的临床应用价值。方法收集本院围产保健门诊孕妇中筛选出符合条件者1 118名,于妊娠16、24、32周进行超声或磁共振检查,观察胎儿脑发育情况,异常者进行干预,出生后的婴儿进行发育随访。结果从1 118名符合条件的观察对象中共检出胎儿脑发育异常者34例。超声或磁共振检出典型脑发育畸形23例,其中15例终止妊娠,8例失去联系;11例轻度脑积水无典型畸形者经干预后,出生胎儿7例发育正常,另4例中2例智力和运动发育稍落后,2例运动落后者经康复治疗达正常水平。结论 MRI是超声发现胎脑异常的重要验证和补充诊断手段。典型的胎脑发育畸形可及时终止妊娠以减少出生缺陷;仅有轻度脑积水不合并脑发育畸形者可以在严密观察中继续妊娠;出生婴儿可以正常发育,部分会有发育落后经康复治疗可达正常儿发育水平。Objective To explore the clinical value of ultrasonic and magnetic resonance imaging（MRI）in the intrauterine fetal encephalodysplasia diagnosis. Methods Among the sampled case,ultrasonic and MRI examinations were conducted to observe the fetal brain development,on gravidas with 16 week,24 week and 32 week pregnancy. Detailed documentations including age,education background,and occupation of the sample gravidas were statistically analyzed.Follow-up visits of sample infants were conducted. Results Among the 2 368 gravidas with the perinatal health care,1 118 cases were sampled in which 34 cases of encephalodysplasia were observed. Specifically,23 cases of typical encephalodysplasia were detected via ultrasonic examinations,among which 15 cases ended with terminations of pregnancy and 8 cases could not be contacted. Moreover,11 mild abnormal cases were under guidance and monitored.According to the results,7 infants grew healthily,while 4 infants were later cured through rehabilitation from growth retardations（2 mental and motor retardation cases and 2 motor retardation cases）. The age and education background of those 34 gravidas with intrauterine fetal encephalodysplasia were analyzed and the result demonstrated a statistical significance（P〈0.05）. Conclusion MRI is an important supplement to ultrasonography in diagnosing fetal abnormality,especially in theintrauterine fetal Encephalodysplasia.The termination of pregnancy is suggested for typical encephalo-dysplasia. For mild hydrocephalus and brain malformation,gestation can continue under close observations.

关 键 词：胎儿发育 超声检查 产前 磁共振成像 

分 类 号：R445[医药卫生—影像医学与核医学] R714.5[医药卫生—诊断学]