双能X线吸收法和生物电阻抗法测量成年超重和肥胖人群骨矿含量的一致性分析  

Comparison BMC assessed by dual-energy X-ray absorptiometry and multi-frequency bioelectrical impedance in Chinese overweight and obesity adults

作　　者：王政和 付连国[2] 阳益德[1] 王烁[1] 马军[1] 

机构地区：[1]北京大学公共卫生学院北京大学儿童青少年卫生研究所,北京100191 [2]蚌埠医学院预防医学系

出　　处：《卫生研究》2016年第3期362-366,共5页Journal of Hygiene Research

摘　　要：目的分析生物电阻抗法(MF-BIA)和双能X线吸收法(DXA)测量成年超重、肥胖人群骨矿含量的一致性,建立MF-BIA法校正预测模型,为MF-BIA法准确测量我国成年超重、肥胖人群的骨矿含量提供依据。方法志愿招募成年超重、肥胖者1323人,分别采用MF-BIA法和DXA法测定受试者的骨矿含量,分析2种方法测量结果的一致性,并建立MF-BIA法校正预测模型。结果 MF-BIA法测量成年超重男性、肥胖男性、超重女性、肥胖女性的骨矿含量与DXA法测量的骨矿含量差值分别为0.28、0.38、0.24和0.36 kg,差异均有统计学意义(P<0.05)。成年超重男性、肥胖男性、超重女性、肥胖女性MF-BIA法与DXA法测量骨矿含量的组内相关系数(ICC)分别为0.787、0.796、0.741和0.788,均有统计学意义(P<0.01)。MF-BIA法校正预测模型为:超重男性人群,骨矿含量(DXA法)=-0.297+1.005×骨矿含量(MF-BIA法);肥胖男性人群,骨矿含量(DXA法)=0.302+0.799×骨矿含量(MF-BIA法);超重女性人群,骨矿含量(DXA法)=0.780+0.598×骨矿含量(MF-BIA法);肥胖女性人群,骨矿含量(DXA法)=0.755+0.597×骨矿含量(MF-BIA法)。结论 MF-BIA法和DXA法测量中国成年超重、肥胖人群骨矿含量一致性较差;在中国成年超重、肥胖人群中,使用MFBIA法测量骨矿含量需进行校正。Objective To compare consistency of Body Mineral Content（ BMC,kg）assessed by Multi-frequency Bioelectrical Impedance Analysis（ MF-BIA） and Dual Energy X- ray Absorptiometry（ DXA） measurement,providing evidence for MF-BIA accurate application in Chinese overweight / obese adults. Methods A total of 1323 overweight / obesity adults aged 22- 55 years were recruited voluntarily. All the subjects received the measurement of BMC both using MF-BIA and DXA. To evaluate the agreement of BMC measured by MF-BIA and DXA using interclass correlation coefficients（ ICC）,then establish correction prediction models. Results The mean difference of BMC between two methods was significant different with 0,overweight male subgroup was 0.28 kg,and 0. 38 kg for obesity male,0. 24 kg for overweight female and 0. 36 kg for obesity female,respectively（ P〈0. 05）. The ICC of BMC between MF-BIA and DXA measurement were statistically significant in all subgroups（ P〈0. 01）. The ICC for overweight male subgroup was 0. 787,0. 796 for obesity male,0. 741 for overweight female and 0. 788 for obesity female, respectively. Correction prediction model：overweight male population： BMC（ DXA method） =- 0. 297 ＋ 1. 005 × BMC（ MF-BIA method）. Obese male population： BMC（ DXA method） = 0. 302 ＋ 0. 799 × BMC（ MFBIA method）. Overweight female groups： BMC（ DXA method） = 0. 780 ＋ 0. 598 × BMC（ MF-BIA method）. Obese female group： BMC（ DXA method） = 0. 755 ＋ 0. 597 × BMC（ MF-BIA method）. Upon examination, correction prediction models were better.Conclusion The correlation and agreement of BMC measured by BIA and DXA are weak in Chinese overweight / obese adults. Therefore,consideration should be given to BMC measured by BIA method in Chinese overweight / obese adults. It should be corrected or adjusted to reduce errors compared with DXA method.

关 键 词：肥胖症 骨矿物质含量 电阻抗 双能X线 预测模型 

分 类 号：R195.2[医药卫生—卫生统计学] R589.2[医药卫生—卫生事业管理]