伴有抑郁症状的2型糖尿病患者控制血糖后抑郁评分的变化  

Change of SDS Following Diabetic Control in T2DM Patients with Depression Symptoms

作　　者：何晓东[1] 石媛[1] 朱筠[1] 曾小云[1] 

机构地区：[1]新疆医科大学第一附属医院内分泌科,乌鲁木齐830054

出　　处：《新疆医学》2015年第12期1738-1739,共2页Xinjiang Medical Journal

摘　　要：目的研究伴有抑郁症状的2型糖尿病患者,随血糖水平改善后,抑郁评分(SDS)的变化情况。方法采用Zung抑郁自评量表在血糖控制不佳的门诊就诊的患者中,筛选出伴有抑郁症状的患者,在积极改善生活方式的基础上予以口服降糖药和/或胰岛素治疗6个月。比较治疗前及治疗后糖化血红蛋白水平(Hb A1c)及SDS。结果共筛选出90例伴有抑郁症状的患者,其中72例完成了随访。72例患者治疗前基线糖化血红蛋白均值为9.32±1.13%,抑郁评分均值为61.74±11.21。经6个月治疗后,糖化血红蛋白水平的均值为7.28±0.41%,SDS均值为51.25±9.28,均较治疗前显著降低,差异均具有统计学意义。结论伴有抑郁症状的2型糖尿病患者,经积极控制血糖水平后,抑郁评分可显著改善。Objective To investigate the change of SDS following diabetic control in T2DM patients accompanied with depression symptoms. Methods Through Zung Self-rating Depression Scale （SDS）, the patients accompanied with depression symptoms were screened in T2DM outpatients with unsatisfactory diabetic control. These patients with both T2DM and depression symptoms were administrated to oral antidiabetic drug and/or insulin and observed for 6 months. The HbAlc, SDS before and after treatment were compared respectively. Results 90 patients were found to accompany depression symptoms, in which 72 completed 6-month observation and foUow-up. The baseline HbAlc and SDS were 9.32 ± 1.13%, 61.74 ± 11.21 respectively. After 6-month of treatment, the mean value of HbAlc significantly decreased to 7.28 ± 0.41%（P〈0.01）, and SDS experienced similar change, the value was 51.25 ± 9.28（P〈0.05）. Conclusion In line with the amelioration of HbAlc level after active hypoglyeemic treatment, the SDS of T2DM with depression symptoms can also fall significantly.

关 键 词：2型糖尿病 抑郁症状 抑郁评分 

分 类 号：R587.1[医药卫生—内分泌]