面向医疗物联网的便携式连续血糖监测系统研究  

Portable Continuous Glucose Monitoring System for Medical Application on Internet of Things

作　　者：蔡丽俊[1,2] 朱志刚[1] 余江渊 李崭虹 葛万成[2] 刘婷玉[3] 

机构地区：[1]上海第二工业大学工学部,上海201209 [2]同济大学电子与信息工程学院,上海201804 [3]上海海事大学高等技术学院,上海200136

出　　处：《传感技术学报》2016年第3期343-348,共6页Chinese Journal of Sensors and Actuators

基　　金：上海高校特聘教授(东方学者)计划;国家自然科学基金(61471233);上海市科委基础研究重点项目(13NM1401300);上海市人才基金(201346);上海市教委曙光计划(14SG52)

摘　　要：本文研制出一种基于物联网的便携式连续血糖监测系统,以实现对糖尿病患者血糖浓度的动态实时监测。整个系统由三部分组成：螺旋型铂-铱电极、血糖信息采集器与网络手持终端。系统在铂-铱工作电极上施加电压激励信号,采集器检测工作-参比电极之间产生的0~1000nA微电流,并转换为相应的血糖浓度信息。本文考察了不同无线传输方式的系统功耗,改进后平均功耗降为0.4mWh左右。检测电路纯阻抗测量误差可控制在1‰左右,葡萄糖溶液实况测试显示,灵敏度为22.8nA/mM。本系统具有便携性、低功耗、智能化与网络化等优点,有望成为一种新型血糖监测仪。The paper develops a portable continuous glucose monitoring system based on Internet of things in order to realize a dynamic continuous monitoring of blood sugar concentration of diabetic patients. The whole system consists of three parts ： a spiral-wired Pt-Ir electrode, a blood sugar information collector and a handheld network device. The system applies a potential signal and the collector thus receives the resulting micro-ampere current （0-1 000 nA）between working and reference electrode and transfers it into relative glucose concentration. System power consumption plays important role to the whole system, and the consumption could be reduced into ca. 0.4 mWh after improvement with different wireless transmission. The pure impedance measurement error of circuits is able to be reduced around 1%o. The real glucose solution test indicates the system have the sensitivity of 22.8 nA/（mmol/L）. This portable system possesses several advantages, such as low power consumption, miniaturization and networking, which are expected to become a novel type of blood sugar monitor.

关 键 词：糖尿病 生物传感器 连续血糖监测 电化学 螺旋电极 物联网 

分 类 号：TN98[电子电信—信息与通信工程]