儿童社区获得性肺炎多重耐药菌的耐药性及高危因素分析  

Analysis on Antibiotics Resistance and Risk Factors of Multidrug-Resistant Bacteria in Community-Acquired Pneumonia in Children

作　　者：陈雅杏 陈影[1] 陆丽苗 

机构地区：[1]肇庆市第二人民医院,广东肇庆526000

出　　处：《临床医学工程》2016年第5期685-686,共2页Clinical Medicine & Engineering

摘　　要：目的探讨儿童社区获得性肺炎多重耐药菌的分布特点、耐药情况及其感染的危险因素。方法回顾性分析121例社区获得性肺炎患儿的病原菌情况,探讨多重耐药菌的危险因素。结果分离出的91株病原菌中多重耐药菌61株,前四位分别为金黄色葡萄球菌(15株)、大肠埃希菌(13株)、肺炎克雷伯菌(10株)、溶血性葡萄球菌(10株)。多因素Logistics回归分析显示幼龄、入院前应用广谱抗生素时间、合并营养不良为多重耐药菌感染的独立危险因素。结论儿童社区获得性肺炎多重耐药菌发生率在逐年升高。幼龄、入院前应用广谱抗生素时间、合并营养不良与患儿发生多重耐药菌感染有密切关系。Objective To investigate the antibiotic resistance distribution and profiles, and risk factors of infection of multidrug-resistant bacteria in community-acquired pneumonia in children. Methods Pathogens from 121 cases of community-acquired pneumonia were analyzed retrospectively, and the risk factors of multidrug-resistant bacteria were analyzed. Results The top four in 61 isolated multidrug-resistant bacteria from 91 isolated pathogenic bacteria were staphyloeoeeusaureus, escherichia coli, klebsiella pneumoniae, and staphylococcus haemolytieus. Multi-factor Logistics analysis revealed that age, time of used broad spectrum antibiotics before admission, and complicated malnutrition were independent risk factors ofmultidrug-resistant bacterial infection. Conclusions There is an increase tendency of multidrug-resistant bacterial infection in community-acquired pneumonia in children. The age, time ＆used broad spectrum antibiotics before admission, and complicated malnutrition are closely related to multidrug-resistant bacterial infection.

关 键 词：儿童 社区获得性肺炎 多重耐药菌 危险因素 

分 类 号：R563.1[医药卫生—呼吸系统]