正交实验优选钩藤中鞣质的提取工艺研究  

THE STUDY OF ORTHOGONAL EXPERIMENT OPTIMIZATION OF UNCARIA TANNIN EXTRACTION TECHNOLOGY

作　　者：王晋[1] 牛梦莉[1] 王静[1] 包小妹[2] 罗素琴[2] 刘勋[2] 王肇辉 刘乐乐[2] 

机构地区：[1]内蒙古医科大学附属人民医院药剂科,内蒙古呼和浩特010020 [2]内蒙古医科大学药学院

出　　处：《内蒙古医科大学学报》2016年第1期39-44,共6页Journal of Inner Mongolia Medical University

基　　金：内蒙古自然科学基金(2012MS1206)

摘　　要：目的:优化钩藤中鞣质的超声提取工艺。方法:以鞣质含量为评价指标,通过正交设计实验筛选出钩藤中鞣质的最佳超声提取工艺。结果:最佳提取工艺为100 m L的90%乙醇作为提取剂,提取时间30 min.结论:通过正交设计实验优选得出的钩藤中鞣质的超声提取工艺条件稳定,为钩藤鞣质进一步研究提供理论参考。Objective：To optimize the ultrasonic extraction technology of tannins in uncaria. Methods：As evaluation index,tannin content was screened by ultrasonic extraction technology through the orthogonal design experiment in uncaria. Results：For optimum extraction process,extracting agent was 100mL 90% ethanol, extraction time was 30 min. Conclusion：The conditions that through orthogonal design experiments in the optimization of uncaria tannins ultrasonic extraction process are stable,and provide theoretical reference for further study on the uncaria tannins.

关 键 词：钩藤鞣质 正交设计 提取工艺 络合滴定法 

分 类 号：R931.5[医药卫生—生药学]