峨眉雪胆微丸对断奶仔猪免疫功能的影响  

Effects of Hemsleya omeiensis pellets on immune function of weaned piglets

作　　者：僧晓兰 李英伦[1] 施飞[1] 何晓利[1] 叶刚[1] 赵玲[1] 

机构地区：[1]四川农业大学动物医学院,四川成都611130

出　　处：《西北农林科技大学学报（自然科学版）》2016年第6期34-39,共6页Journal of Northwest A&F University(Natural Science Edition)

基　　金：四川省科技支撑计划项目"中兽药创制与产业应用"(2013NZ0019)

摘　　要：【目的】研究峨眉雪胆微丸对断奶仔猪免疫功能的影响。【方法】将96头"杜×长×大"三元杂交断奶仔猪随机分为4组,每组24头,分别饲喂基础日粮、基础日粮+硫酸粘杆菌素80mg/kg、基础日粮+峨眉雪胆微丸250mg/kg、基础日粮+峨眉雪胆微丸500mg/kg的试验日粮,试验期为21d,分别于饲喂后的第7,14和21天采集血样和肠黏膜,测定断奶仔猪的免疫功能指标,研究峨眉雪胆微丸对断奶仔猪免疫功能的影响。【结果】日粮中添加250mg/kg峨眉雪胆微丸可促进血清免疫球蛋白IgG、IgM、IgA的生成,显著提高补体C3、C4及免疫因子IL-6的质量浓度(P<0.05),并可在一定程度上降低炎性因子IL-1β的分泌,提高十二指肠、回肠、盲肠的免疫球蛋白A(SIgA)分泌,其中对十二指肠、盲肠SIgA的分泌有显著促进作用(P<0.05)。【结论】日粮中添加250mg/kg峨眉雪胆微丸可增强断奶仔猪的免疫功能。[Objective] The effects of Hemsleya omeiensis pellets on immune function of weaned piglets were reported in this paper. [Method] A total of 96 weaned crossbred piglets at the age of 28 days were randomly divided into 4 groups, with 3 replicates per group and 8 piglets per replicate. In blank control group, piglets were fed with basal diet. The experimental group was fed with same basal diet supplemented with 250 mg/kg and 500 mg/kg Hemsleya omeiensis pellets while the control group was fed with supple- ments of 80 mg/kg Sulfate coli element. After 21 days,the intestinal mucosa and blood samples were col- lected and used to represent immune function. [Result] Adding 250 mg/kg Hemsleya omeiensis pellets to diets of weaned piglets increased serum IgG, IgM, and IgA, significantly increased concentrations of comum,ileum, and cecum was increased as well, especially for duodenum and ce- cum （P〈0.05）. [Conclusion] Adding 250 mg/kg Hemsleya omeiensis pellets to diets enhanced immune function of weaned piglets.

关 键 词：断奶仔猪 峨眉雪胆微丸 免疫功能 免疫球蛋白 黏膜免疫 

分 类 号：S858.283.72[农业科学—临床兽医学] S816.7[农业科学—兽医学]