射频消融术在良性甲状腺结节中的应用(附119例报告)  

Application of radiofrequency ablation of benign thyroid nodules (Report of 119 cases)

作　　者：叶晓楠[1] 翟军伟[2] 苏子剑[1] 潘群雄[1] 李明珠[1] 曾志雄[3] 王聪仁[1] 柯少迎[1] 

机构地区：[1]福建医科大学附属泉州市第一医院肿瘤外科,福建泉州362000 [2]山东省滕州市中心人民医院外科,山东滕州277500 [3]福建医科大学附属泉州市第一医院彩超室,福建泉州362000

出　　处：《中国肿瘤外科杂志》2016年第2期99-103,共5页Chinese Journal of Surgical Oncology

基　　金：福建省自然科学基金(2014J01435);泉州市科技计划项目(2013Z58)

摘　　要：目的研究彩超引导下射频消融(radiofrequency ablation,RFA)治疗甲状腺良性结节的临床效果。方法整理2013年1月至2014年6月对泉州市第一医院119例甲状腺良性结节在基础麻醉下行彩超引导下的RFA治疗,术后随访症状体征改善、有无并发症,彩超监测结节大小、计算体积缩小率,分析影响消融效果的相关因素,每例均规则随访1年以上。结果所有病例均顺利行RFA,术后随访结节体积明显缩小(P<0.05),血流信号减少或消失,症状体征明显改善。术中无严重并发症发生,术后出现2例声音嘶哑,随访3个月后均恢复正常。结论彩超引导下RFA治疗甲状腺良性结节疗安全、微创,术后疗效好,无明显并发症及后遗症,是值得临床推广的治疗甲状腺良性结节的非手术方法。Objective To study the clinical effect of ultrasound guided radiofrequency ablation（ RFA） for benign thyroid nodules. Methods Analysis were conducted on 119 patients with benign thyroid nodules for ultrasound guided radiofrequency ablation therapy under basic anesthesia from January 2013 to June 2014. The nodule size in ultrasound,symptoms and cosmetic scores were evaluated before and after RFA,the nodule volume reduction rate was calculated,and the related complications and related factors of efficacy were assessed during follow up. Each case was followed up for more than 1 year regularly. Results All cases were successful treated with RFA. After treatment,all thyroid nodules in size to different degree（ P〈0. 05）,blood flow signals in nodules decreased or disappeared,symptoms and cosmetic scores were obviously reduced. No patient experienced a serious complication during therapy. Two patients experienced transient voice changes,and recovered spontaneously within 3 months after treatment. Conclusions Ultrasound guided RFA may be an safe and effective nonsurgical alternative in the treatment of benign thyroid nodules. There were no life-threatening complications or sequelae. Therefore,RFA is clinically prospective for application.

关 键 词：射频消融 甲状腺良性结节 超声引导 

分 类 号：R581[医药卫生—内分泌]