^(99m)Tc-HMPAO SPECT rCBF显像对难治性癫痫诊断价值的探讨  

The exploration on diagnostic values of 99m Tc-HMPAO SPECT rCBF imaging in medically intractable epilepsy.

作　　者：周列民[1] 黄如训[1] 李沂[2] 曾世莹 石锐[2] 

机构地区：[1]中山医科大学附属一院神经科 [2]中山医科大学附属一院核医学科

出　　处：《中国神经精神疾病杂志》1991年第4期218-221,共4页Chinese Journal of Nervous and Mental Diseases

摘　　要：对27例难治性癫痫进行了发作间期^(99m)Tc-HMPAO SPECT rCBF显像,X线CT和EEG检查。结果表明:27例中有24例rCBF明显减少,癫痫病灶检出率为88.89％。定位诊断显著优于X线CT,头皮电极EEG以及蝶骨电极EEG描记。其中13例复杂部分发作rCBF显像示病灶多数位于颞叶,但是也可见于额叶和顶叶。本结果还提示:简单部分性发作,复杂部分性发作或复杂部分性发作继发大发作多数病灶局限,适宜手术治疗。99m Tc-HMPAO SPECT rCBF imaging, X-rays CT scans and EEGs were performed on 27 patients with medically intractable epilepsy during the interictal period. The results indicated that the rCBF decreased remarkably in the 24/27 patients and the detected rate of epileptic focus was 88.89%. Compared with X-rays CT scans and scalp or sphenoid electrode EEGS, SPECT seemed to show more significances in discovering the abnormalities in the epileptics. Among 13 patients with Complex Partial Seizure (CPS), SPECT rCBF showed that the most of epileptic foci were localized at temporal lobe, sometimes at frontal or parietal lobe. It was suggested that due to localizing epileptic foci, it was suitable for the patients with Simple Partial Seizure (SPS), CPS and CPS-Secondarily Generalized Seizure (SecGS) to be operat-ed.

关 键 词：癫痫 放射性核素 诊断 

分 类 号：R817.41[医药卫生—影像医学与核医学]