双侧原发性乳腺癌13例临床病理分析  

Clinicopathological features of bilateral primary breast cancer

作　　者：田青青[1] 刘杰[1] 袁静萍[1] 

机构地区：[1]武汉市中心医院病理科,武汉430014

出　　处：《诊断病理学杂志》2016年第5期324-327,共4页Chinese Journal of Diagnostic Pathology

基　　金：湖北省武汉市卫生局立项课题(WX12C58);湖北省自然科学基金课题(2013CFB374)

摘　　要：探讨双侧原发性乳腺癌（BPBC）的临床病理特征。方法收集13例BPBC的临床病理资料,观察和分析其临床病理特征并随访。结果 13例BPBC均为女性,其中同时性BPBC 4例,异时性BPBC 9例。BPBC首发癌与次发癌的ER、PR、Her-2的表达较一致。13例均获随访,其中3例死亡,10例存活,存活时间为4-78个月。结论正确积极治疗BPBC,其5年生存率与单侧乳腺癌相同。首发癌后5年是预防的重点。Objective To investigate the clinicopathological features of bilateral primary breast cancer（BPBC）.Methods The clinicopathological features were collected and followed up in 13 cases of intermuscular BPBC. Results All patients were female.4（30. 8%） cases presented synchronous bilateral primary breast cancer（sBPBC）,and 9（69. 2%） developed metachronous bilateral primary breast cancer（mBPBC）. The first cancer and the second cancer of BPBC had resemblance in ER,PR and Her-2 states. Follow-up information was available in 13 patients,and 10 of them were still alive（survived for 4 to 78 months） and the other 3 were died. Conclusion If treatment is correct for BPBC,its 5-year survival rate is same as unilateral breast cancer.Five years after the first primary breast cancer is the focus of prevention.

关 键 词：原发性乳腺癌 临床病理 预后 

分 类 号：R737.9[医药卫生—肿瘤]