午睡与高血压的相关性  

Association between siesta and hypertension

作　　者：孙训明 胡淑娟[1] 姚舜[1] 刘足云[1] 杨亚军[1,2] 袁子宇[2] 金力[1] 王笑峰[1,2] 

机构地区：[1]复旦大学生命科学学院现代人类学教育部重点实验室流行病学室,上海200438 [2]复旦大学泰州健康科学研究院

出　　处：《中华高血压杂志》2016年第4期329-333,共5页Chinese Journal of Hypertension

基　　金：国家科技支撑项目(2011BAI09B00);国家自然科学基金面上项目(81571372)

摘　　要：目的探讨午睡对发生高血压的影响。方法用横断面调查收集35~64岁江苏省泰州地区14 413人资料,采用Logistic回归分析计算自报午睡者（n=6561）相对于不午睡者（n=7852）发生高血压的风险。结果午睡者的收缩压水平略低于不午睡者[（135.7±20.1）比（137.3±19.8）mm Hg,P〈0.01]。有午睡的女性血压水平明显低于不午睡女性[收缩压（132.7±20.3）比（136.3±20.5）mm Hg,P〈0.01;舒张压（78.6±11.6）比（80.2±11.7）mm Hg,P〈0.01],且在多因素调整的方差分析中差异仍有统计学意义（均P〈0.01）。调整年龄、婚姻状况、教育程度,吸烟、饮酒、体质量指数（BMI）、空腹血糖、三酰甘油等之后,Logistic回归分析结果显示在女性中午睡明显降低高血压发生风险（OR=0.897,95%CI0.813~0.989）。进一步按照是否绝经分层,显示这种午睡降低高血压风险的效应出现在绝经前女性中（OR=0.817,95%CI 0.704~0.949）。午睡与高血压的相关结果在男性中未观察到。结论对于绝经前的泰州地区部分中年女性,午睡可能对高血压的发生起保护作用。Objective To investigate the effect of siesta on the occurrence of hypertension. Methods Data of14 413 subjects,aged 35-64 years old,recruited from Taizhou city in Jiangsu province,were collected with the cross-sectional survey method. Multivariate logistic regression analysis was used to calculate odds ratio of hypertension among people who were reported to have a siesta（n=6561）compared others with no siesta（n=7852）.Results Systolic blood pressure（SBP）of subjects taking a siesta was slightly lower than those of no siestas[（135.7±20.1）vs（137.3±19.8）mmHg,P0.01]. Of females,both systolic and diastolic blood pressures（DBP）with siesta were significantly lower than those without[SBP（132.7±20.3）vs（136.3±20.5）mm Hg,P0.01;DBP（78.6±11.6）vs（80.2±11.7）mm Hg,P0.01]. After adjusting other factors in analysis of covariance,there were still statistically significant differences（P0.01）. After adjusting for age,marriage status,education level,smoking,alcohol intake,body mass index（BMI）,fasting blood-glucose and triacylglycerol,logistic regression analysis showed that the risk of hypertension among females with siesta were significantly decreased（OR=0.897,95% CI0.813-0.989）. More importantly,stratificating by menopause status in further,data indicated that the association between siesta and decreasing risk of hypertension was appeared in the premenopausal women（OR=0.817,95% CI0.704-0.949）. But this association was not observed among males. Conclusion For some middle-aged premenopausal females in Taizhou area,siesta may have a protectional effect on the occurrence of hypertension.

关 键 词：高血压 午睡 横断面调查 中年女性 绝经 

分 类 号：R544.1[医药卫生—心血管疾病]