苗药乌纠治疗大鼠疮疡模型活性部位研究  

Research on Active Part Form Miao Medicine Wet Jiub on Cure Rat Sore Model

作　　者：孟铁宏[1] 李春荣[1] 王恒[1] 

机构地区：[1]黔南民族医学高等专科学校公共课教学部化学教研室,贵州都匀558000

出　　处：《哈尔滨医药》2016年第2期101-103,共3页Harbin Medical Journal

基　　金：黔南民族医学高等专科学校基金(QNYZ201319);黔南民族医学高等专科学校基金(QNYZ201510);贵州省厅校科技联合基金(Gzwkj2012-2-018)

摘　　要：目的确定苗药乌纠治疗疮疡活性成分所在部位。方法采用金黄色葡萄球菌感染大鼠制作疮疡模型,通过与空白组和模型组比较,观察苗药乌纠不同提取活性部位对大鼠疮疡模型体征、愈合情况、脏器指数及血清中溶菌酶的影响。结果苗药乌纠不同提取活性部位组均能有效提高大鼠疮疡模型血清中的溶菌酶含量和胸腺指数及脾脏指数,增强大鼠疮疡模型的免疫功能,其中石油醚提取活性部位和正丁醇提取活性部位对溶菌酶提高最大,对大鼠疮疡模型治疗效果最为显著。结论苗药乌纠治疗疮疡活性成分主要集中在石油醚提取活性部位和正丁醇提取活性部位。Objective To determine the active position of wet jiub on cure rat sore model. Methods Establishing sores ulcers rats model,compared with blank and model groups,to observe the effect of rats sore model,wound healing,viscera index and serum lysozyme in different active positon of wet jiub. Results The different active position effectively improve the content of serum lysozyme,thymus index,spleen index,enhance the immune function of rats sore model,petroleum ether extract andn- butanol extract effect are remarkable to improve the serum lysozyme and cure the rats sore model. Conclusion The activeingredients of cure sore mainly in petroleum ether extract and n- butanol extract from wet jiub.

关 键 词：乌纠 活性部位 疮疡模型 

分 类 号：R932[医药卫生—生药学]