过度换气综合征患者手足搐搦危险因素分析  

To analyze the risk factors of tetany in patients with hyperventilation syndrome

作　　者：游道锋[1] 乔秋阁[2] 谢冰[1] 姜相明[1] 陈莹[1] 

机构地区：[1]河北医科大学第一医院急诊科,050031 [2]河北医科大学第二医院东院普外科

出　　处：《天津医药》2016年第6期763-765,共3页Tianjin Medical Journal

基　　金：河北省卫计委重点科技研究计划(ZD20140508)

摘　　要：目的探讨引起过度换气综合征患者出现手足搐搦的危险因素。方法分析就诊于我院的过度换气综合征患者103例,根据其是否出现手足搐搦,分为手足搐搦组和非手足搐搦组。分析2组之间性别、年龄、电解质、p H值和二氧化碳分压[p(CO2)]的差异;将P<0.1的因素纳入二分类Logistic回归,并采用Logistic回归(Forward Wald法)分析患者出现手足搐搦的危险因素。结果 103例患者中出现手足搐搦者70例(68%),未出现33例(32%),手足搐搦组血清K+、血清磷和p(CO2)均明显低于非手足搐搦组(P<0.01),而手足搐搦组p H值高于非手足搐搦组(P<0.01)。2组性别、年龄、血清Na+、血清Cl-、血清钙(结合钙和离子Ca2+)、离子Ca2+和血清Mg2+水平差异无统计学意义(P>0.05)。二分类Logistic回归分析显示年龄小、血清K+降低、血清磷降低和p(CO2)降低是手足搐搦的危险因素。结论年龄小、血清K+水平降低、血清磷降低和p(CO2)降低是过度换气综合征患者出现手足搐搦的危险因素。Objective To explore the risk factors causing tetany in patients with hyperventilation syndrome. Meth?ods A total of 103 patients with hyperventilation syndrome treated in our hospital were included in this study. According to whether there was tetany, patients were divided into tetany group and non-tetany group. Values of gender, age, electrolyte, pH and p(CO2) were analysed between two groups. The factors of P<0.1 were engaged in binary Logistic regression. Logistic regression (Forward Wald) was used to analyze the risk factors of tetany in patients with hyperventilation syndrome. Re?sults In 103 patients there were 70 patients with tetany (68%), 33 patients without tetany(32%). The serum K+, serum phos?phorus and p(CO2) values were significantly lower in tetany group than those of non-tetany group (P<0.01), while the pH value was significantly higher in tetany group than those of non-tetany group (P<0.01). There were no significant differences in gen?der, age, serum Na+, serum Cl-, serum calcium (bound calcium and ionized calcium), ionized calcium and serum Mg2+levels be?tween two groups (P>0.05). It was revealed that the younger age, the lower level of the serum K+, serum phosphorus and p(CO2) were the risk factors of tetany through binary Logistic regression analysis. Conclusion The risk factors of tetany in patients with hyperventilation syndrome include younger age, lower level of serum K+and serum phosphorus and reduced p(CO2).

关 键 词：通气过度 手足搐搦 低钙血症 低磷血症 低钾血症 血气分析 危险因素 

分 类 号：R563[医药卫生—呼吸系统]