颈动脉内膜剥脱术治疗症状性颈动脉狭窄的临床效果  

Effect of carotid endarterectomy for the treatment of symptomatic carotid artery stenosis

作　　者：杨茜[1] 严臻泉[1] 吴国斌[1] 张博[1] 柳晓锋[1] 

机构地区：[1]河北省石家庄市第一医院神经内科,河北石家庄050011

出　　处：《中国医药导报》2016年第14期57-60,共4页China Medical Herald

基　　金：河北省科技支撑计划项目(12276104D-13)

摘　　要：目的探讨颈动脉内膜剥脱术治疗症状性颈动脉狭窄患者的临床效果。方法选取2011年7月~2014年1月石家庄市第一医院神经科住院的症状性颈动脉狭窄患者68例,分为手术组和非手术组,颈动脉内膜剥脱术治疗组（手术组）23例,内科保守治疗组（非手术组）45例。观察两组患者手术/治疗后短期疗效、住院时间、住院费用;记录随访一年脑卒中复发率、死亡率。结果手术组患者治愈率（47.83%）及显效率（47.83%）高于非手术组的治愈率（13.33%）和显效率（44.44%）,无效率（4.34%）低于非手术组（42.22%）（P=0.001）;手术组患者住院时间（36.5±5.6）d短于非手术组[（44.8±6.7）d]（P=0.001）,住院费用[（51 200±230）元]低于非手术组[（67 900±470）元]（P=0.001）;随访一年,手术组患者脑卒中复发率（8.69%）低于非手术组（42.22%）（P=0.005）,死亡率（4.34%）低于非手术组（24.44%）（P=0.040）,差异均有统计学意义。结论对于症状性颈动脉狭窄患者,颈动脉内膜剥脱术治疗效果好,安全有效,经济适用。Objective To explore effect of carotid endarterectomy for the treatment of symptomatic carotid artery stenosis. Methods 68 cases of patients with symptomatic carotid stenosis in the First Hospital of Shijiazhuang neurologist hospital from July 2011 to January 2014 were selected and divided into surgical and non surgical group, carotid endarterectomy treatment group（surgical group） 23 cases, internal medicine conservative treatment group（non surgical group） 45 cases. The short-term curative effect after surgery/treatment, the length of hospital stay, hospital expenses of two groups of patients were observed; Cases were followed up for stroke recurrence rate and mortality rate. Results The patients surgical group cure rate（47.83%） and efficiency rate（47.83%） were higher than those of non surgical group（13.33%, 44.44%）, no efficiency rate（4.34%） was lower than that of non surgical group（42.22%）（P=0.001）; The surgical patients in hospital [（36.5±5.6） days] was shorter than those of non surgical group [（44.8±6.7） days]（P=0.001）, hospitalization costs [（51 200±230） yuan] was lower than those of non surgical group [（67 900±470） yuan]（P=0.001）; Follow-up for a year, score in patients of surgical group with stroke recurrence rate（8.69%） was lower than that of non surgical group（42.22%）（P=0.005）, death rate（4.34%） was lower than that of non surgical group（24.44%）（P=0.040）,the difference was statistically significant. Conclusion Effect of carotid endarterectomy for the treatment of patients with symptomatic carotid artery stenosis is good, safe, effective and economical.

关 键 词：颈动脉内膜剥脱术 症状性颈动脉狭窄 效果 

分 类 号：R651.1[医药卫生—外科学]