株洲市无偿献血者HIV感染率及初筛与确证试验结果分析  

Volunteer blood donors' HIV infection rate and the analysis of screening and confirmatory test results in Zhuzhou

作　　者：熊志高 刘昕晨 谭艳阳 

机构地区：[1]株洲市中心血站,湖南株洲412007

出　　处：《中国输血杂志》2016年第4期406-408,共3页Chinese Journal of Blood Transfusion

摘　　要：目的了解株洲市无偿献血者中的HIV感染率,分析HIV检测初筛与确证试验结果的相关性。方法对2008年10月至2015年5月株洲市中心血站的无偿献血者血液样本进行"双人双盲法"HIV初筛,任何1种试剂HIV初筛检测阳性的标本均进行确证试验,统计HIV阳性生率,并分析初筛与确证试验结果的相关性。结果研究期间230 882位无偿献血者中共有397例HIV初筛阳性,其中45例两次ELISA检测均为阳性,45例ELISA双阳标本中80%(36例)确证试验阳性,13.3%(6例)确证试验结果为不确定,6.67%(3例)确证试验阴性;另有1例ELISA单试剂初筛阳性标本确证检测为阳性。结论双试剂阳性和确证阳性之间存在着极显著的正相关关系,且较高的S/CO值预示HIV抗体阳性的可能性大。Objective To analyze the correlation between HIV screening test results and confirmatory test results,in order to know about the HIV infection rate of volunteer blood donors in Zhuzhou city. Methods Volunteer blood donors＇ samples with different reagent were screened by different laboratory technicians from October 2008 to May 2015 in Zhuzhou Central Blood Station. The samples that have been detected positive by any of two reagents in screening test would then conduct confirmatory test. HIV positive incidence rate was calculated and the correlation between screening and confirming test results was analyzed. Results There were 397 HIV screening positive cases among 230 882 donors during the study period,including 45 positive cases from screening and confirmatory ELISA test,among which,80%（ 36 cases） were determined by the ELISA confirmatory test,13. 3%（ 6 cases） were uncertain and 6. 67%（ 3 cases） were negative. There was another positive case screened by both single reagent ELISA test and the confirmatory test. Conclusion There is a significant positive correlation between the positive result in the double reagents test and the confirmatory test. High S / CO value indicates high possibility of positivity for HIV antibody.

关 键 词：无偿献血者 HIV初筛 确证试验 

分 类 号：R446.6[医药卫生—诊断学] R512.91[医药卫生—临床医学]