机构地区:[1]深圳市第二人民医院康复医学科,广东深圳518035
出 处:《心血管康复医学杂志》2016年第3期229-234,共6页Chinese Journal of Cardiovascular Rehabilitation Medicine
摘 要:目的:研究基于运动负荷试验评估的个性化有氧运动对急性心肌梗死(AMI)患者心功能与心理状态的疗效。方法:选择80例恢复期的AMI患者为研究对象,采用随机数字表法,患者被均分为常规治疗组(40例,接受常规药物治疗)和运动组(40例,在常规治疗组基础上接受基于运动负荷试验评估的个性化有氧运动)。比较两组患者干预前、干预12周后的血清高敏心肌肌钙蛋白I(hs-cTnI)和肌酸激酶同工酶(CK-MB)水平,左室射血分数(LVEF)、每博量(SV)、左室短轴缩短率(LVFS)、室壁增厚率(△T)、室间隔运动幅度(AIS),以及焦虑自评量表(SAS)和抑郁自评量表(SDS)评分。结果:与干预前比较,干预12周后两组的血清hs-cTnI和CKMB水平均明显降低,SAS和SDS评分亦均显著降低;LVEF,SV,LVFS,△T和AIS均显著升高(常规治疗组的LVEF除外),P<0.05或<0.01;且与常规治疗组比较,运动组血清hs-cTnI[(9.31±1.04)ng/L比(5.89±0.72)ng/L]和CK-MB水平[(11.34±1.25)U/L比(8.41±1.01)U/L];SAS[(51.34±6.54)分比(42.32±5.29)分]和SDS[(50.23±6.92)分比(43.86±6.03)分]评分降低更显著,LVEF[(57.12±6.67)%比(62.32±7.34)%],SV[(62.45±7.13)ml比(69.18±7.84)ml],LVFS[(23.93±2.96)%比(28.45±3.12)%],△T[(28.51±3.41)%比(34.52±4.87)%]和AIS[(9.56±1.02)mm比(12.45±1.46)mm]升高更显著,P<0.05或<0.01。结论:基于运动负荷试验评估的个性化有氧运动能够减轻心肌细胞损伤、改善心脏功能、缓解负面情绪,促进患者迅速康复。Objective: To study therapeutic effect of personalized aerobic exercise based on ement on heart function and psychological state in patients with acute myocardial infacording to random number table,a total of 80 AMI patients during recovery period were randomly and equally divided into routine treatment group (n = 40,received routine drug therapy) and exercise group (n=40,received personalized aerobic exercise based on exercise loadest assessment on the basis of routine treatment groof high-sensitivity cardiac troponin I (hs-cTnI) and creatine kinase isoenzyme MB (CK-MB) , and left ventricular ejection fraction (LVEF), stroke volume (SV), left ventricular fractional shortening (LVFS), ventricular wall thickening rate (AT),motion amplitude of interventricular septum (AIS),and scores of self-rating anxiety scale (SAS) and self-rating depression scale (SDS) were compared between two groups before and after 12-week interven-tion. Results: Compared with before intervention,there were significant reductions in serum levels of hs-cTnI and CK-MB,and scores of SAS and SDS; and significant rise in LVEF,SV,LVFS,A T and AIS in 12-week intervention (except LVEF of routine treatment group),P 〈 0 . 05 or 〈 0 . 01 ; compared with routine treat mentgroup,therewere significantreductions in serum levels of hs-cTnI [ (9.31±1.04) ng/Lvs. (5.89±0.72) ng/ L] andCK-MB [ (11.34±1.25) U/Lvs. (8.41±1.01) U/L],in scores of SAS [ (51.34±6.54) scores vs. (2. 32 ±5.29) scores] and SDS [ (50.23±6.92) scores vs. (43.86±6.03) scores]; and significant rise±6.67)% vs. (62.32±7.34)%],SV [ (62.45±7.13) ml vs. (69.18±7.84) ml],LVFS [ (23.93±2.96)% vs. (28.45±3.12)%],AT [ (2 8 .5 1± 3 .4 1 )% vs. (3 4 .5 2± 4 .8 7 )%] andAIS [ (9 .5 6 ± 1 .0 2 ) mmvs. (1 2 .4 5± 1.4 6 ) mm] in exercise group,P〈0.05 or〈0.01. Conclusion: Personalized aerobic exercise based on exercise load tes
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