氨基糖苷类药物的危害及其检测方法研究进展  

Review on Hazards and Detection Methods of Aminoglycoside Antibiotics

作　　者：高月[1] 王耀[1] 胡骁飞[2] 邓瑞广[2] 侯玉泽[1] 

机构地区：[1]河南科技大学食品与生物工程学院/畜禽疫病诊断与食品安全检测河南省工程实验室,河南洛阳471023 [2]河南省农业科学院动物免疫学重点实验室,河南郑州450002

出　　处：《河南农业科学》2016年第6期9-14,共6页Journal of Henan Agricultural Sciences

基　　金：国家科技支撑计划项目(2014BAD13B05);公益行业(农业)科研专项(201203040);河南科技大学博士科研启动基金项目(13480062)

摘　　要：氨基糖苷类药物是一个种类丰富的抗生素类别,因其能防治某些动物性疾病且能促进动物的生长发育,在养殖业中应用广泛。但长期高剂量使用该类药物,会因其降解困难对环境造成危害,并且可通过食物链传递给人。该类药物能够在人体内蓄积,从而产生耳毒性、肾毒性等危害。因此,检测食物中氨基糖苷类药物的残留十分必要。对氨基糖苷类药物的危害及其检测方法进行综述,并对其未来发展方向进行展望。Aminoglycoside drugs are a wide variety of antibiotics. They have been widely used in animal husbandry and aquaculture for this class of antibiotics which can prevent some kind of animal diseases,and promote animal growth and development. But if these drugs were used for a long term with high dose,it would cause harm to the environment because of its bad degradation ability,and it could transmit to people by food chain. More serious was the accumulation of the drug in the body,which would produce ototoxicity,kidney toxicity and other hazards to the human body. Therefore,the detection of residues of these drugs in food was essential. In this paper,the hazards and the detection methods of aminoglycoside antibiotics were reviewed,and a preliminary outlook for future development of the detection were conducted.

关 键 词：氨基糖苷类药物 危害 检测方法 

分 类 号：S859.84[农业科学—临床兽医学]