冠脉斑块形态与血管活性因子相关性研究  

To Study the Correlation Between Coronary Plaque Morphology and Vascular Active Factors

作　　者：李培英[1] 陈云龙[1] 郭益红[1] 吴志坚[1] 

机构地区：[1]福建医科大学附属三明第一医院干部病房,福建三明365000

出　　处：《中国继续医学教育》2016年第12期63-64,共2页China Continuing Medical Education

基　　金：福建医科大学非直属附属医院科研发展专项课题(FZS 13033Y)

摘　　要：目的探讨冠心病的斑块形态与血管活性因子ET1、NO、CGRP相关性。方法选取60例冠状动脉粥样硬化性心脏病患者,根据斑块形态学分为I型组18例、II型组28例、III型组14例,比较三组血管活性因子ET1、NO、CRRP、ET1/NO、ET1/CGRP、NO/CGRP水平情况。结果病理形态I型、II型和III型间ET1和CGRP差异存在统计学意义(P<0.05),NO、ET1/NO、ET1/CGRP和NO/CGRP差异无统计学意义(P>0.05)。结论血管活性因子水平与冠心病斑块形态具有一定的相关性。Objective To explore the plaque morphology of coronary heart disease and vascular active factor ET1, NO, CGRP correlation. Methods 60 cases of coronary atherosclerotic heart disease, according to the plaque morphology can be divided into type Ⅰ 18 cases, type Ⅱ group 28 cases, 14 cases of type Ⅲ group, compare the three groups of vascular active factor, NO, ET1 CRRP, ET1/NO, ET1/CGRP and NO/CGRP level. Results Pathological morphology between type Ⅰ and type Ⅱ and type Ⅲ ET1 and CGRP statistical differences（P〈0.05）, NO, ET1/NO, ET1/CGRP and NO/CGRP no statistical difference（P〉0.05）. Conclusion Vascular active factor level and coronary heart disease（CHD） plaque morphology has a certain relevance.

关 键 词：冠心病 斑块形态 血管活性因子 

分 类 号：R541[医药卫生—心血管疾病]