颅内外联合血管重建术治疗烟雾病的疗效  

Efficacy of combined inside and outside revascularization in improving neurological function of moyamoya disease

作　　者：蒋锋[1] 高嵘[1] 刘惠祥[1] 赵旦[1] 徐平[1] 钱晓波[1] 张立[1] 孙晓锋[1] 李建[1] 

机构地区：[1]张家港市第一人民医院神经外科,江苏省215600

出　　处：《江苏医药》2016年第9期1009-1011,F0003,共4页Jiangsu Medical Journal

摘　　要：目的观察颅内外联合血管重建术治疗烟雾病的临床疗效。方法收集56例烟雾病患者的临床资料,患者均接受颞浅动脉-大脑中动脉搭桥加脑-硬脑膜-肌肉血管融合术,采用改良Rankin量表(mRS)评分进行评估神经功能,分析手术前后神经功能变化。结果患者手术均未出现颅内出血及脑梗死的不良并发症。影像学检查显示,吻合血管均通畅,术后3个月神经功能较术前得到显著改善。患者术后1周mRS评分(2.84±1.46)分,术后3个月为(1.38±1.13)分,低于术前1d的(3.08±1.31)分(P<0.05)。结论联合血管重建术治疗烟雾病可有效改善患者的神经功能状况。Objective To observe the clinical efficacy of combined inside and outside cranial revascularization of（STA-MCA＋EDMS）in improving neurological functions of patients with moyamoya disease.Methods Clinical data of 56 patients with moyamoya disease received STA-MCA anastomosis and EDMS were collected.The neurological function was evaluated by modified Rankin scale（mRS）and the changes of neurological function before and one week and three months after surgery were analyzed.Results The intracranial bleeding and cerebral infarct did not occurr after surgery in all cases.CTA or DSA after operation showed that STA-MCA anastomosis was patent and neurological functions were significantly improved in all cases with decreased mRS scores of（2.84±1.46）points 1week and（1.38±1.13）points 3 months compared to（3.08±1.31）points before operation 1d（P〈0.05）.Conclusion STA-MCA＋EDMS surgery can effectively improve the neurological functions in the patients with Moyamoya disease.

关 键 词：血管重建术 烟雾病 

分 类 号：R651[医药卫生—外科学]