T_(12)椎体前缘不同压缩状态下相邻椎体终板应力的有限元分析  

Finite element analysis of stress of the adjacent vertebral end plate of T_(12) vertebral body in different compression states

作　　者：冯杰荣[1] 殷海东[1] 陈伟[1] 黄明光[1] 

机构地区：[1]南方医科大学附属顺德第一人民医院,广东省佛山市528300

出　　处：《中国组织工程研究》2016年第22期3263-3271,共9页Chinese Journal of Tissue Engineering Research

基　　金：佛山市卫生与计生局医学科研课题(2015236)~~

摘　　要：背景:椎体压缩骨折是老年骨质疏松症患者最常见的脊柱骨折,椎体前缘的压缩程度与邻近椎体再骨折是否相关尚未明确。目的:利用有限元方法建立T_(12)椎体前缘不同压缩状态模型,并分析T_(12)椎体前缘压缩程度与邻椎终板应力的相关性。方法:基于正常成年人志愿者的胸腰段CT数据,导入MIMICS/3-matic,经图像分割、修补及三维网格化获取胸腰椎T_(11)-L1节段数据,网格赋材质属性后导入ABAQUS,建立韧带、小关节等特征,获取逼真的三维有限元模型。对模型前屈、后伸、左侧屈、右侧屈、左旋及右旋等6个自由度进行加载,验证正常模型的有效性。分别将T_(12)椎体前缘压缩至90%,80%,70%……10%共9个状态,提取T_(11)下终板及L1上终板的MISES应力,获得压缩状态与邻近终板应力的关系曲线。结果与结论:1该模型高度逼真,能真实反映实际受力状态;2结果表明,T_(11)椎体下位终板和L1椎体上位终板的应力值与T_(12)椎体前缘的压缩程度呈正相关,应力增加可能导致终板骨折的可能性增加,进而增大相邻椎体的骨折风险。BACKGROUND：Vertebral compression fractures are the most common vertebral fractures in the elderly patients with osteoporosis,and the correlation between the compression of anterior border of vertebral body and adjacent vertebral refractures is not clear.OBJECTIVE：To establish a model of different compression of T（12） vertebral body with finite element method,and analyze the relationship between the compression of T（12） vertebral body and the stress of adjacent vertebral plate.METHODS：Based on thoracolumbar CT data of normal adult volunteers,MIMICS/3-matic was imported.Through image segmentation,repair and three-dimensional mesh of access to thoracic and lumbar T（11）-L1 data,grid assigned material properties was imported to ABAQUS so as to establish ligament,joint and other small features and obtain realistic three-dimensional finite element model.The six degrees of freedom,including anteflexion,posterior extension,left and right flexion,left and right rotation,were loaded,to verify the validity of the normal model.With the frontier of vertebral body compression to 90%,80%,70%…10% of the nine states,MISES stresses of the T（11） and L1 segment intervertebral disc endplate were extracted;the relationship curve of compression state and endplate stress was obtained.RESULTS AND CONCLUSION：（1） The model was highly realistic and could reflect the actual stress state.（2） The stress value of T（11） vertebral body and L1 vertebral body was positively correlated with the compression of T（12） vertebral body.Increased stress may lead to an increased likelihood of end plate fractures,which increases the risk of fractures in the adjacent vertebral bodies.

关 键 词：胸椎 腰椎 应力 物理 有限元分析 组织工程 骨科植入物 脊柱植入物 胸腰椎 ABAQUS 三维模型 压缩状态 终板应力 

分 类 号：R318[医药卫生—生物医学工程]