非布司他治疗痛风伴高尿酸血症疗效观察  

Efficacy of Febuxostat Tablets in the Treatment of Gout and Hyperuricemia

作　　者：谷丽梅[1] 

机构地区：[1]四平市中心人民医院风湿免疫科,吉林四平136000

出　　处：《中国卫生标准管理》2016年第7期106-107,共2页China Health Standard Management

摘　　要：目的分析非布司他治疗痛风伴高尿酸血症的临床效果。方法按照入院顺序将我院2011年5月~2015年11月收治的105例痛风伴高尿酸血症患者随机分为观察组（n=52）及对照组（n=53）。观察组采用非布司他治疗,对照组采用别嘌醇治疗,对比两组患者接受治疗后血尿酸的变化情况。结果观察组患者接受治疗之前的血尿酸值为（523.75±36.42）μmol/L,治疗之后的血尿酸值为（328.63±29.18）μmol/L。而对照组患者接受治疗之前的血尿酸值为（534.28±33.09）μmol/L,治疗之后的血尿酸值为（374.52±31.54）μmol/L。观察组患者的治疗情况优于对照组（P〈0.05）。结论采用非布司他治疗痛风伴高尿酸血症能够降低患者的血尿酸水平,改善患者的临床症状,提高患者的生活质量。Objective To analyze the clinical effect of febuxostat in the treatment of gout and hyperuricemia. Methods According to the order of admission,105 cases of gout and hyperuricemia were randomly divided into observation group（n=52）and control group（n=53）in our hospital from May 2011 to November 2015. The observation group using the febuxostat treatment,control group was treated with allopurinol treatment,compared two groups of patients after treatment serum uric acid changes. Results In the observation group,the serum uric acid level was（523.75±36.42）mol/L before treatment,the serum uric acid value was（328.63±29.18）mol/L. While the control group received treatment before the blood uric acid value was（534.28±33.09）mol/L,after the treatment of blood uric acid value was（374.52±31.54）mol/L. The treatment of observation group was significantly better than the control group（P 〈 0.05）. Conclusion The treatment of gout with hyperuricemia can significantly reduce the level of serum uric acid,improve the clinical symptoms of patients,improve the quality of life of patients.

关 键 词：非布司他 痛风伴高尿酸血症 疗效观察 

分 类 号：R983[医药卫生—药品]