人工关节置换术后感染的预防、诊断和治疗研究进展  

Research progress of prevention,diagnosis and treatment in the infection after artificial joint replacement

作　　者：张鑫[1] 李慧娟[1,2] 周亮[1] 王明媚[1] 王心慧[1] 卫晋菲[1] 刘皈阳[1] 李春平[2] 

机构地区：[1]中国人民解放军总医院第一附属医院药剂药理科,北京100048 [2]邯郸市第一医院药学部,河北邯郸056000

出　　处：《实用药物与临床》2016年第5期639-643,共5页Practical Pharmacy and Clinical Remedies

摘　　要：人工关节感染是人工关节置换术后最严重的并发症,一旦发生感染,会给患者带来巨大的身体负担和经济压力,除此之外,人工关节感染的诊断治疗难度较大,且大量抗菌药物的使用会使细菌耐药性增加,因此,必须了解人工关节置换术中导致感染的危险因素,及时采取预防措施,清楚实验室检查诊断的内容,还要严格按照细菌培养、药敏试验的结果合理选择抗菌药物,避免细菌耐药率的增加。另外,抗生素骨水泥的应用也作为重点研究的内容,本文针对这些问题进行扼要综述。The patients will bear huge body burden and economic pressure if the infection of artificial joint, the most serious complication after artificial joint replacement,occurred. Besides, the diagnosis and treatment of artificial joint infection are difficult, and a large number of antibacterial agents can result in the growth of bacterial resistance.Therefore, it is important to understand the risk factors for infection in artificial joint replacement, take timely preventive measures, clear the contents of the laboratory diagnosis,and reasonably choose antibacterial agents which are in strict accordance with the results of bacterial culture and drug sensitivity test to avoid increasing the drug resistance rate. In addition, the application of antibiotic-loaded bone cement has also been focused. In this paper, some brief points which are aiming at these problems are reviewed.

关 键 词：人工关节感染 危险因素 细菌培养 药敏试验 抗生素骨水泥 

分 类 号：R687.4[医药卫生—骨科学]