人猪链球菌感染的临床实验室诊断研究进展  

Research advances in clinical laboratory diagnosis of Streptococcus suis infection

作　　者：刘海珠[1] 袁晓明 

机构地区：[1]大连医科大学附属威海市立医院检验科,威海264200 [2]山东省荣成市虎山畜牧兽医站,荣成264300

出　　处：《中国人兽共患病学报》2016年第5期490-493,共4页Chinese Journal of Zoonoses

摘　　要：猪链球菌(S.suis)是一种重要的人兽共患病原菌,可感染人并导致严重的脑膜炎、败血症,甚至引起死亡。自1968年国际首次发现了2型猪链球菌引起人类严重感染的病例以来,国内外又有诸多相关报道。人类在感染该菌的早期并无特异性表现,但病情进展迅速,若不及时诊断并予以干预,死亡率较高。2005年6月至8月在四川省资阳、内江等地区相继暴发人感染猪链球菌病疫情,广泛引起了国内外的关注。由于S.suis不仅给养猪业造成很大威胁,而且严重危害公共卫生安全,对该菌进行准确的早期诊断是控制猪链球菌病流行的关键。目前,针对该病原体的常见实验室检测方法包括微生物检测法、免疫学检测法、分子生物学检测法及动物实验法等。本文将就人感染S.suis的实验室诊断研究进展做一简要综述。Streptococcus suis（S.suis）is an important pathogen of zoonotic infectious diseases.Once human being suffered fromS.suis,it will cause severe meningitis,septicemia,sometimes even cause death.Many related reports have been covered since Streptococcus suis serotype 2was found to cause serious infection in human being for the first time in 1968.It is a rapiddeveloping critical disease with a high mortality and has nonspecific clinical symptoms at the early stage.An outbreak of people infected with S.suis in Ziyang and Neijiang of Sichuan Province from June to August 2005 had aroused extensive attention.S.suis is not only greatly harmful to culturist,but also underlying dangerous to public health security,so timely and early diagnoses have become the key question to control the prevalent of S.suis.At present,the common laboratory detection methods include microbial detection,immunoassay,molecular biological test and animal experiment method.This article reviews progress in the research of laboratory diagnosis of human infected with S.suis.

关 键 词：猪链球菌 人兽共患病原菌 实验室诊断 

分 类 号：R378[医药卫生—病原生物学]