多焦点和单焦点非球面人工晶状体置入治疗老年性白内障后视觉功能的比较  

Visual function of senile cataract patients after implantation of an aspheric multifocal versus an aspheric monofocal intraocular lens

作　　者：王国强[1] 赵燕[1] 赵延涛[1] 丁颖[1] 

机构地区：[1]河北医科大学第一医院眼科,河北省石家庄市050081

出　　处：《中国组织工程研究》2016年第21期3171-3177,共7页Chinese Journal of Tissue Engineering Research

基　　金：河北省医学科学研究重点课题计划(20140099)~~

摘　　要：背景:单焦点人工晶状体能够恢复白内障患者的远视力,但近视力恢复较差,多数仍需要佩戴眼镜;多焦点人工晶状体可弥补单焦点人工晶状体的不足,改善近视力,提高脱镜率。目的:比较多焦点和单焦点非球面人工晶状体置入治疗老年性白内障后的视觉功能。方法:将35例(50眼)老年白内障患者分为2组,试验组置入多焦点非球面人工晶状体,对照组置入单焦点非球面人工晶状体。置入后3个月,检测5 m裸眼远视力和最佳矫正远视力,30,60,100 cm裸眼近、中视力,以及明暗环境中0.8,1.5,6,18 cpd空间频率下的对比敏感度。结果与结论:置入后3个月,两组5 m裸眼远视力均较置入前明显改善(P<0.05),两组间5 m、100 cm裸眼远中视力比较差异无显著性意义,但试验组30,60 cm裸眼近视力高于对照组(P<0.05)。两组明环境下不同空间频率的对比敏感度无差异;试验组暗环境下6 cpd空间频率的对比敏感度低于对照组(P<0.05),两组其余频率下的对比敏感度无差异。结果表明,相较于单焦点非球面人工晶状体,多焦点非球面人工晶状体可有效改善患者的裸眼近、中视力。BACKGROUND： Monofocal intraocular lens can restore distant vision of cataract patients, but it is not suitable for near vision recovery, so most of patients still need to wear glasses. In contrast, multifocal intraocular lens can make up for the shortcomings of the single lens to improve near vision and increase the rate of taking off the spectacles. OBJECTIVE： To compare the visual function of senile cataract patients after aspheric multifocal and monofocal intraocular lens implantation. METHODS： Totally 30 senile cataract patients with 50 affected eyes were randomly divided into two groups： the eyes were implanted with aspheric multifocal and monofocal intraocular lens as experimental group and control group, respectively. At 3 months after implantation, distance visual acuity at a distance of 5 m, the best corrected distance visual acuity, as well as near and intermediate visual acuity at a distance of 30, 60 and 100 cm were detected, respectively. Besides, contrast sensitivity at a spatial frequency of 0.8, 1.5, 6 and 18 cpd under light and dark environment was measured. RESULTS AND CONCLUSION： At 3 months after implantation, the distance visual acuity at a distance of 5 m in the two groups was significantly better than that before surgery（P〈0.05）; no significant differences were found in near and intermediate visual acuities at a distance of 5 m and 100 cm between two groups, but the near visual acuities at a distance of 30 and 60 cm in the experimental group were significantly higher than those in the control group（P〈0.05）. In addition, the contrast sensitivity at different spatial frequencies under light environment had no significant differences between two groups; and compared with the control group, contrast sensitivity at the frequency of 6 cpd under dark environment was significantly decreased in the experimental group（P〈0.05）, but no significant differences were found in the other spatial frequencies. These results show that aspheric multifocal intraocular lens can signifi

关 键 词：晶体 人工 白内障 对比敏感度 组织工程 生物材料 材料相容性 多焦点 单焦点 人工晶状体 球面 非球面 老年性 视觉功能 

分 类 号：R318[医药卫生—生物医学工程]