长沙市健康人群心电图长／短校正QT间期出现率及临床意义  

Incidence and clinical significance of long and short corrected QT interval in electrocardiogram in Changsha healthy people

作　　者：刘丽萍[1] 林萍[1] 邹润梅[1] 吴礼嘉[1] 毛定安[1] 谢振武[1] 王成[1] 

机构地区：[1]中南大学湘雅二医院儿童医学中心儿童心血管专科 中南大学儿科学研究所,长沙410011

出　　处：《中华心律失常学杂志》2016年第2期145-148,共4页Chinese Journal of Cardiac Arrhythmias

基　　金：湖南省发展改革委员会课题[湘财企指（2015）83号]

摘　　要：目的探讨长沙市健康人群12导联体表心电图长／短校正QT间期的出现率及其临床意义。方法选择1993年1月至2012年12月在中南大学湘雅二医院进行健康检查的4025例出生6min至83岁长沙市居民。描记12导联体表心电图，测量心率、QT间期，利用Bazett’s平方根校正公式计算校正的QT间期（QTc=QT／RR0.5）。利用SPSS16．0软件进行统计学处理。结果短QTc总出现率为7．13％（287／4025），在18—29岁、30～39岁、40～49岁年龄组达高值（分别为15．09％、15．71％、13．11％），在1～2个月、3～5个月年龄组达低值（分别为0、0．76％）。长QTc总出现率为3．16％（127／4025），儿童期（〈18岁）各年龄组差异无统计学意义，进入成人期后出现率突然显著下降，在18～29岁、30～39岁年龄组达低值（分别为0．86％、0．71％），50岁以后又逐渐增高，在50～59岁、60～69岁、70～83岁年龄组达高值（分别为7．89％、9．06％、14．06％）。男女长／短QTc出现率差异无统计学意义（P〉0．05）。结论长／短QTc在健康人群存在两个年龄高峰，30～39岁是短QTc出现率高峰，50岁后是长QTc出现率高峰，对于这两个年龄组需重点关注QTc变化，防止心血管事件发生。Objective To explore the incidence and clinical significance of long/short corrected QT interval （QTc） from standard 12-lead electrocardiogram record in Changsha healthy population. Meth- ods Standard 12-lead electrocardiograms were recorded on 4 025 Changsha population aged from 6 min to 83 years old between Jan 1993 to Dec 2012. Heart rate and QT interval were measured, QTc was calculated by Bazett＇s formula （QTc = QT/RR0. 5）. All individuals were taken healthy examination in the Second Xiangya Hospital of Central South University. Statistical analyses were performed with the SPSS 16. 0 software. Results The incidence of short QTc was 7. 13% （287/4 025）. The peak value of incidence were in the 18- 29 years old group,30-39 years old group and 40～49 years old group （15.09%, 15.71%, 13.11% ,respec- tively）. The low values were in the 1 ～ 2 month group, 3- 5 month group （0 and 0.76%）. The incidence of long QTc was 3.16% （127/4 025）. There was no statistical difference among the childhood groups. The value dropped significantly suddenly after entering adulthood. The low values were in the 18-29 years old group,30～ 39 years old group （0. 86% ,0. 71% ）. The incidence of long QTc increased with age since entering 50 years old （7. 89% ,9. 06%, 14. 06%, respectively）and there was no statistical differences between gender （P〉0. 05）. Conclusion Long/short QTc existed in Changsha healthy population in two age groups. The peak incidence of short QTc was in 30 ～ 39 years old group, the peak incidence of long QTc was in the period of older than 50 years old. For these two age groups,it was recommended to focus on the change of QTc to prevent cardiovascular events.

关 键 词：心电图 长校正QT间期 短校正QT间期 

分 类 号：R540.41[医药卫生—心血管疾病]