机构地区:[1]青海省心脑血管病专科医院放射科,西宁810012
出 处:《中华心血管病杂志》2016年第5期426-430,共5页Chinese Journal of Cardiology
摘 要:目的探讨中高海拔地区汉族与藏族人群冠状动脉畸形的差异。方法入选2010至2015年所有在青海省心脑血管病专科医院行冠状动脉CT血管成像且居住在青海高原(海拔1800—7720m)的成年人7028名,进行回顾性分析。其中,汉族6391名,藏族637名。通过分析冠状动脉CT血管成像结果,比较汉族与藏族人群的冠状动脉畸形特征差异。结果(1)汉族人群的冠状动脉畸形发生率为1.596%(102/6391),藏族人群的冠状动脉畸形发生率为4.239%(27/637),差异有统计学意义(P〈0.001)。(2)汉族的冠状动脉畸形患者中男性占64.7%(66/102),藏族的冠状动脉畸形患者中男性占74.1%(20/27),差异无统计学意义(P:0.359)。(3)汉族患者中冠状动脉畸形发生在左侧占64.4%(67/104),藏族患者中冠状动脉畸形发生在左侧占55.6%(15/27),差异无统计学意义(P=0.396)。(4)汉族人群的良性冠状动脉畸形发生率为0.720%(46/6391),藏族人群的良性冠状动脉畸形发生率为2.200%(14/637),差异有统计学意义(P〈0.001);汉族人群的潜在危险冠状动脉畸形发生率为0.876%(56/6391),藏族人群的潜在危险冠状动脉畸形发生率为2.041%(13/637),差异有统计学意义(P=0.004)。(5)共发现冠状动脉畸形10种,其中,左冠状动脉起源于右冠状动脉窦[汉族为0.046%(3/6391)、藏族为0.471%(3/637),P=0.012]、左回旋支起源于右冠状动脉窦[汉族为0.046%(3/6391)、藏族为0.471%(3/637),P=0.012]、右冠状动脉开口于左冠状动脉窦或左前降支[汉族为0.704%(45/6391)、藏族为1.570%(10/637),P=0.018]的发生率汉族和藏族之间差异有统计学意义。结论中高海拔地区藏族人群的冠状动脉畸形发生率高于汉族人群,良性冠状动�Objective To analyze the differences of coronary artery anomalies between Han and Tibetan nationality living in middle and high altitude. Methods A total of 7 028 adults living in the Qinghai Plateau ( 1 800--7 720 m altitude) , who underwent coronary CT angiography in Qinghai Cardio- cerebro-vascular Disease Special Hospital between 2010 to 2015, were included in this study. There were 6 391 cases of the Han nationality and 637 cases of the Tibetan nationality. The differences of coronary artery anomalies between klan and Tibetan nationality were analyzed retrospectively. Results ( 1 ) Incidence of coronary artery anomalies was lower in Han nationality than in the Tibetan nationality ( 1. 596% ( 102/6 391 ) vs. 4. 239% (27/637) ,P 〈 0. 001 ). (2) There was 64. 7% (66/102) male residents with coronary artery anomalies in Han nationality, and 74. 1% (20/27) male residents with coronary artery anomalies in Tibetan nationality ( P = 0. 359 ). ( 3 ) Left side coronary artery anomalies in Han nationality was similar as in Tibetan nationality (64.4% (67/104) vs. 55.6% (15/27) , P =0. 396). (4) Incidence of benign coronary artery anomalies was significantly lower in Han nationality than in Tibetan nationality (0. 720% (46/6 391 ) vs. 2. 200% ( 14/637 ) , P 〈 0. 001 ) . Incidence of potentially dangerous coronary artery anomalies was also significantly lower in Han nationality than in Tibetan nationality (0. 876% (56/6 391 ) vs. 2.041% (13/637) , P =0. 004). (5)Ten kinds of coronary artery anomalies were found in this study. There were significant differences between Han and Tibetan nationality in left coronary artery originated from right coronary sinus(O. 046% (3/6 391 ) vs. 0. 471% (3/637) ,P =0. 012), in left circumflex branch originated from right coronary sinus ( 0. 046% ( 3/6 391 ) vs. 0. 471% ( 3/637 ), P = 0. 012 ), and opening of right coronary artery in left coronary sinus or left anterior descending
分 类 号:R543.3[医药卫生—心血管疾病]
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