BR-TRG-I型体腔热灌注治疗仪实施膀胱内温热灌注化疗的疗效观察  

Effect of BR-TRG-I body cavity hyperthermic perfusion instrument on intravesical chemotherapy

作　　者：李斌[1] 夏桃林[1] 

机构地区：[1]佛山市第一人民医院泌尿外科,广东佛山528000

出　　处：《临床泌尿外科杂志》2016年第5期419-421,共3页Journal of Clinical Urology

摘　　要：目的：探讨BR-TRG-I型体腔热灌注治疗仪实施膀胱内温热灌注化疗治疗高复发表浅性膀胱移行细胞癌的效果。方法：选取2011年3月～2014年10月收治的高复发表浅性膀胱移行细胞癌患者90例,随机分为研究组（n=45）和对照组（n=45）。对照组患者术后24小时内行膀胱灌注,研究组患者术后3天行丝裂霉素膀胱腔内热灌注化疗。结果：研究组患者膀胱局部复发率为33.3%（15/45）,显著低于对照组的77.8%（35/45）（P〈0.05）;复发时间和复发间期均显著长于对照组（P〈0.05）;复发肿瘤个数显著少于对照组（P〈0.05）。结论：BR-TRG-I型体腔热灌注治疗仪实施膀胱内温热灌注化疗治疗高复发表浅性膀胱移行细胞癌患者效果显著,值得在临床推广。Objective：To investigate the effect of BR-TRG-I body cavity hyperthermic perfusion instrument on intravesical chemotherapy in the treatment of highly recurrent superficial bladder transitional cell carcinoma.Method：From March 2011 to October 2014,90 patients with highly recurrent superficial bladder transitional cell carcinoma in our hospital were randomly selected,and they were divided into study group（n=45）and control group（n=45）.The control group were given intravesical perfusion within 24 hours postoperatively,while the study group were given intravesical mitomycin perfusion three days postoperatively.Result：Local recurrence rate of bladder of the study group was 33.3%（15/45）,which was significantly lower than that of the control group 77.8%（35/45）（P〈0.05）.Moreover,in study group the time of relapse and recurrence interval were significantly longer（P〈0.05）.Also,the number of tumor recurrence of study group was significantly less than that of the control group（P〈0.05）.Conclusion：The effect of BR-TRG-I body cavity hyperthermic perfusion instrument on intravesical chemotherapy in the treatment of highly recurrent superficial bladder transitional cell carcinoma is significant,and it＇s worth popularizing.

关 键 词：膀胱肿瘤 移行细胞癌 BR-TRG-I型体腔热灌注治疗仪 

分 类 号：R737.14[医药卫生—肿瘤]