感兴趣区大小对单源双能CT能谱成像CT值及水(碘)浓度值影响  

Influence of the Size of Regions of Interest on CT Value and Material Decomposition Measurement in Water Phantom by Single-source Dual Energy CT

作　　者：刘泽群[1] 孙美玉[1] 刘爱连[1] 韩铮[1] 

机构地区：[1]大连医科大学附属第一医院,辽宁大连116011

出　　处：《CT理论与应用研究（中英文）》2016年第2期129-134,共6页Computerized Tomography Theory and Applications

基　　金：国家自然科学基金(84170078)

摘　　要：目的:应用单源双能CT对标准水膜进行能谱扫描,探讨不同大小感兴趣区(ROI)对CT值及宝石能谱成像(GSI)水(碘)浓度值的影响。方法:利用GSI模式扫描标准水膜,层厚1.25 mm,间距1.25 mm。扫描参数:扫描视野medium,转速0.8 s/转,螺距0.984,探测器宽度40 mm,电流550 m A。以水膜中心为圆心,在水膜中心位置分别画两个面积为(600±30)mm2、(3 000±30)mm2的ROI,分别为ROI1、ROI2。将单能量图像(70ke V)载入能谱成像分析软件GSI viewer进行分析,分别测量ROI1、ROI2的CT值(HU)、水(碘)值(mg/cm3)并记录,统计学分析采用配对样本t检验,若P<0.05为差异有统计学意义。结果:ROI1的平均CT值为(2.45±1.83)HU,ROI2的平均CT值为(2.55±1.68)HU,两者之间的差异无统计学意义(P=0.06);ROI1的平均水(碘)值为(1 001.22±0.86)mg/cm3,ROI2的平均水(碘)值为(1 001.31±0.84)mg/cm3,两者之间的差异无统计学意义(P=0.135)。结论:改变ROI大小不影响单源双能CT图像中CT值和水(碘)含量的测定。Objective： To investigate the effect of different size of Region of interest（ROI） on CT value and material decomposition measurement in the standard water phantom using single-source dual-energy CT. Methods： The standard water phantom provided by GE company was scanned by single-source dual-energy CT machine（Discovery CT 750 HD, America GE Company）. The image processing was performed on GSI Viewer browser to acquire and record CT value（HU）, the concentration value of water-iodine（mg/cm3）. The scanning parameters were as follows： scanning visual field： medium, rotating speed of 0.8 seconds/rotation, pitch 0.984, detector width 40 mm, current： 550 m A. The two drawn ROIs were round, located in the central part of the water phantom. Their areas were（600 ± 30） mm2 and（3 000 ± 30） mm2, and then recorded as ROI1 and ROI2 respectively. Paired sample t test was used for statistical analysis. Results： ROI1 CT value was（2.45 ± 1.83） HU, ROI2 CT value was（2.55 ± 1.68） HU, there was no statistical significance between CT value of ROI1 and ROI2（P = 0.06）; The water-iodine value was（1 001.22 ± 0.86） mg/cm3 in ROI1, and that of ROI2 was（1 001.31 ± 0.84） mg/cm3, there was no statistical significance between water iodine value of ROI1 and ROI2（P = 0.135）. Conclusions： Different ROI size will have no effect on the measurement of CT value and the concentration of water-iodine from single-source dual energy CT.

关 键 词：GSI CT值 水(碘)浓度值 感兴趣区大小 

分 类 号：R814.42[医药卫生—影像医学与核医学]