肠外营养临床应用分析  

Clinical application analysis of parenteral nutrition drugs

作　　者：杨传英[1] 杨静[1] 李淑珍[1] 宋超[1] 

机构地区：[1]山东省交通医院药剂科,山东省济南250031

出　　处：《中国基层医药》2016年第11期1624-1628,共5页Chinese Journal of Primary Medicine and Pharmacy

基　　金：中国药学会科技开发中心委托研究项目（2012DCST04EM03）

摘　　要：目的调查分析肠外营养药的临床应用情况，促进合理用药。方法采用回顾性调查方式，统计2015年肠外营养药品应用情况，包括使用量、使用金额、使用范围等，同时进行用药合理性分析。结果根据患者基础代谢值设计的脂肪乳氨基酸17葡萄糖11％注射液1440mL、脂肪乳氨基酸（18）注射液1000mL临床消耗量远远大于代谢轻度增加值设计的1920mL；而平衡性氨基酸制剂以复方氨基酸以18AA—Ⅳ使用量远大于18AA—Ⅱ及18AA。脂肪乳制剂以20％浓度的用量较大，因价格优势，普通长链脂肪乳使用量大于中长链脂肪乳。在用药合理性方面，着重对肠外营养适应证、用法用量、配伍、不良反应进行分析，在用药剂量、频次、配伍等方面仍存在问题，还需改进。结论该院肠外营养的使用基本合理，但应严格控制肠外营养支持的适应证，在药品配伍、使用频次等药物合理应用方面加强管理，提高用药安全性。Objective To investigate the clinical application of parenteral nutrition.drugs and promote the rational use of drugs. Methods The data of parenteral nutrition drugs used in our hospital were analyzed, including the quantity, the amount of money, the scope and purpose, etc. The rationality of drug use was reviewed by prescription comment simultaneously. Results On similar medicines comparison, the fat emulsion, amino acids （ 17 ） and glucose （11%） injection （1440mL） and fat emulsion and amino acids （18） injection （1 000mL）,which were designed according to the basal metabolic rate in patients were far greater than the fat emulsion, amino acids （17） and glucose （11%） injection （1 920mL） of the added value of design. And the balanced amino acid preparations in compound amino acid in 18 AA - Ⅳ usage,was far greater than 18 AA - Ⅱ and 18 AA. Fat emulsion preparation with concentration of 20% dosage was bigger, because the price advantage, ordinary long -chain fat milk consumption was greater than the long chain fatty milk. In terms of drug use rationality, the usage, dosage, compatibility and adverse reactions of parenteral nutrition drugs were analyzed. The dosage, frequency and compatibility problems still needed to be improved. Conclusion The use of parenteral nutrition drugs were basic reasonable,but we should strictly control the indications for parenteral nutrition support, such as drug compatibility, using frequency to strengthen management and reasonable application of drugs to improve medication safety.

关 键 词：肠外营养 处方点评 合理用药 

分 类 号：R459.3[医药卫生—治疗学]