七氟醚复合舒芬太尼与氯胺酮麻醉对疝气腹腔镜手术患儿的临床效果及血液流变学分析  

Clinical effects and hemodynamic changes in children after sevoflurane-sufentanil and ketamine anesthesia for laparoscopy of hernia

作　　者：蒋文军[1] 杨孟昌[2] 徐冰[1] 

机构地区：[1]四川省人民医院儿外科,四川成都610072 [2]四川省人民医院麻醉科,四川成都610072

出　　处：《中国医院药学杂志》2016年第10期838-840,共3页Chinese Journal of Hospital Pharmacy

基　　金：四川省技术创新资助项目(编号:2013EF00167)

摘　　要：目的:观察比较七氟醚复合舒芬太尼对比氯胺酮全身麻醉在小儿疝气腹腔镜手术中的临床效果及血液流变学变化。方法:将60例行疝气腹腔镜手术的患儿随机分为2组,分别为观察组30例,采用面罩吸入七氟醚复合静脉滴注舒芬太尼进行麻醉;对照组30例,采用氯胺酮肌内注射进行麻醉。观察2组患儿麻醉诱导时间、苏醒时间、手术时间、不良反应情况及麻醉前后患儿血液流变学指标心率(HR)、平均动脉压(MAP)、血氧饱和度(SpO2)变化。结果:观察组与对照组相比,观察组麻醉诱导时间、苏醒时间更短,不良反应情况更少,差异存在统计学意义(P<0.05),手术时间差异不存在统计学意义;血液流变学指标HR、MAP、SpO22组变化差异不存在统计学意义(P>0.05)。结论:应用七氟醚复合舒芬太尼进行小儿疝气腹腔镜手术的麻醉效果更好,具有麻醉诱导时间短,苏醒快,手术时间短,不良反应少的特点,值得临床推广。OBJECTIVE To compare anesthetic effects of sevoflurane-sufentanil and ketamine for laparoscopy of hernia in children.METHODS A total of 60 children with hernia were randomly divided into observation group and control group with30 cases in each group.Children in observation group received inhalation anesthesia with sevoflurane and intravenous instillation of sufentanil.Children in control group received anesthesia with intramuscular ketamine.In two groups of children,annesthesia induction time,recovery time,operation time,adverse events,and hemodynamic indicators in laparoscopic procedures were observed,including heart rate（HR）,mean arterial pressure（MAP）and oxygen saturation（SpO2）.RESULTS Anesthesia induction time,recovery time and adverse events were significantly shorter in observation group than control group（P0.05）.While operation time showed no statistical significance（P〈0.05）.HR,MAP and SpO2 of two groups had no statistical significance（P〉0.05）.CONCLUSION Sevoflurane-sufentanil used for pediatric hernia anesthesia is better with a short induction time,a fast recovery time,and a low incidence of adverse reactions,which is worthy of promotion.

关 键 词：七氟醚 舒芬太尼 氯胺酮 疝气 腹腔镜 

分 类 号：R969[医药卫生—药理学]