高尿酸血症与H型高血压早期动脉粥样硬化的相关性  

The correlation study of hyperuricemia and early atherosclerosis with H type hypertension

作　　者：葛余浩 严光 刘丽萍 顾辨辨 郑辉 

机构地区：[1]安徽医科大学附属省立医院干部二病区,合肥230001 [2]安徽医科大学附属省立医院医学影像中心,合肥230001 [3]安徽医科大学附属省立医院医学检验中心,合肥230001

出　　处：《安徽医科大学学报》2016年第6期900-903,共4页Acta Universitatis Medicinalis Anhui

基　　金：国家"十二五"科技支撑项目:中国重要心血管病患病率调查及关键技术研究(编号:2011BAI11B01)

摘　　要：将70例干部保健男性人群,根据同型半胱氨酸(Hcy)水平≥10μmol/L以及血尿酸(UA)≥420μmol/L选择H型高血压合并高尿酸血症组30例、H型高血压病组20例、单纯原发性高血压组20例,比较不同组间各代谢指标及颈动脉内膜中层厚度(IMT)。结果显示IMT在男性H型高血压合并高尿酸血症组比H型高血压病组、单纯原发性高血压组均显著增高(P<0.05),提示尿酸升高为H型高血压IMT的独立危险因素(P<0.05),易导致动脉粥样硬化形成。Seventy male patients in health care for cadres were enrolled and divided into three groups according tothe levels of serum uric acid and homocysteine： H type hypertension and hyperuricemia group（ n = 30）; H type hypertension（ n = 20）; simple hypertension（ n = 20）. The differences of blood pressure,blood glucose,blood lipid and intima-media thickness among groups were analyzed. IMT was significantly higher in H type hypertension and hyperuricemia group compared with the other two groups（ P〈 0. 05）. Hyperuricemia was the independent risk factor for IMT（ P 〈0. 05） and more prone to atherosclerosis in H type hypertension.

关 键 词：血尿酸 高血压 动脉粥样硬化 

分 类 号：R543.5[医药卫生—心血管疾病]